N | Metabolites | Association with: | |||||
---|---|---|---|---|---|---|---|
BMI | Â | WC | Â | WHR | Â | ||
β (95% CI) | p* | β (95% CI) | p* | β (95% CI) | p* | ||
1 | Asparagine | − 1.02 (− 1.25; − 0.79) | < .001 | − 1.11 (− 1.38; − 0.84) | < .001 | − 0.80 (− 1.15; − 0.45) | < .001 |
2 | Glutamine | − 0.83 (− 1.05; − 0.60) | < .001 | − 0.92 (− 1.18; − 0.65) | < .001 | − 0.69 (− 1.03; − 0.35) | < .001 |
3 | Glutamate | 1.03 (0.83; 1.23) | < .001 | 1.08 (0.84; 1.32) | < .001 | 0.64 (0.33; 0.95) | < .001 |
4 | Glycine | − 1.01 (− 1.24; − 0.79) | < .001 | − 1.31 (− 1.57; − 1.04) | < .001 | − 1.40 (− 1.74; − 1.05) | < .001 |
5 | Isoleucine | 1.04 (0.80; 1.27) | < .001 | 1.24 (0.95; 1.52) | < .001 | 1.03 (0.66; 1.39) | < .001 |
6 | Serine | − 0.93 (− 1.15; − 0.71) | < .001 | − 1.02 (− 1.29; − 0.76) | < .001 | − 1.04 (− 1.38; − 0.69) | < .001 |
7 | Valine | 1.35 (1.12; 1.58) | < .001 | 1.49 (1.22; 1.77) | < .001 | 1.17 (0.82; 1.53) | < .001 |
8 | LysoPC a C17:0 | − 1.14 (− 1.35; − 0.92) | < .001 | − 1.31 (− 1.56; − 1.05) | < .001 | − 0.82 (− 1.15; − 0.48) | < .001 |
9 | LysoPC a C18:1 | −1.36 (− 1.57; − 1.16) | < .001 | − 1.51 (− 1.75; − 1.27) | < .001 | − 0.97 (− 1.28; − 0.65) | < .001 |
10 | LysoPC a C18:2 | − 1.47 (− 1.68; − 1.25) | < .001 | − 1.59 (− 1.85; − 1.33) | < .001 | − 1.00 (− 1.34; − 0.66) | < .001 |
11 | PC aa C38:3 | 1.69 (1.46; 1.92) | < .001 | 1.85 (1.57; 2.12) | < .001 | 1.62 (1.27; 1.98) | < .001 |
12 | PC aa C38:4 | 1.06 (0.83; 1.30) | < .001 | 1.26 (0.98; 1.54) | < .001 | 1.20 (0.84; 1.56) | < .001 |
13 | PC aa C42:0 | − 0.22 (− 0.27; − 0.17) | < .001 | − 0.26 (− 0.32; − 0.20) | < .001 | − 0.23 (− 0.31; − 0.15) | < .001 |
14 | PC ae C34:3 | − 1.26 (− 1.49; − 1.03) | < .001 | − 1.7 (− 1.97; − 1.42) | < .001 | − 1.77 (− 2.12; − 1.42) | < .001 |
15 | PC ae C40:5 | − 1.06 (− 1.29; − 0.83) | < .001 | − 1.24 (− 1.51; − 0.97) | < .001 | − 0.99 (− 1.34; − 0.64) | < .001 |
16 | PC ae C42:5 | − 1.13 (− 1.35; − 0.91) | < .001 | − 1.34 (− 1.6; − 1.08) | < .001 | − 1.14 (− 1.48; − 0.8) | < .001 |
17 | Acylcarnitine C0 | 0.85 (0.61; 1.09) | < .001 | 0.92 (0.64; 1.21) | < .001 | – | – |
18 | Acylcarnitine C3 | 0.27 (0.14; 0.41) | < .001 | 0.34 (0.18; 0.49) | < .001 | – | – |
19 | Acylcarnitine C5 | 0.69 (0.51; 0.86) | < .001 | 0.63 (0.42; 0.83) | < .001 | – | – |
20 | Leucine | 1.09 (0.85; 1.33) | < .001 | 1.23 (0.95; 1.52) | < .001 | – | – |
21 | Phenylalanine | 0.78 (0.55; 1.01) | < .001 | 0.88 (0.61; 1.15) | < .001 | – | – |
22 | Tyrosine | 1.23 (0.98; 1.47) | < .001 | 1.22 (0.92; 1.51) | < .001 | – | – |
23 | Kynurenine | 1.10 (0.87; 1.33) | < .001 | 0.96 (0.68; 1.23) | < .001 | – | – |
24 | PC aa C32:1 | 0.58 (0.36; 0.81) | < .001 | 0.46 (0.20; 0.73) | 0.001 | – | – |
25 | PC aa C34:4 | 0.57 (0.32; 0.81) | <. 001 | 0.44 (0.15; 0.73) | 0.004 | – | – |
26 | PC aa C38:0 | − 0.46 (− 0.68; − 0.24) | <. 001 | − 0.62 (− 0.88; − 0.36) | < .001 | – | – |
27 | PC aa C40:2 | − 0.11 (− 0.17; − 0.05) | < .001 | − 0.14 (− 0.21; − 0.08) | < .001 | – | – |
28 | PC aa C40:4 | 0.61 (0.36; 0.85) | < .001 | 0.78 (0.50; 1.07) | < .001 | – | – |
29 | PC aa C40:6 | 0.73 (0.49; 0.96) | < .001 | 0.76 (0.49; 1.04) | < .001 | – | – |
30 | PC aa C42:1 | − 0.12 (− 0.15; − 0.09) | < .001 | − 0.15 (− 0.18; − 0.11) | < .001 | – | – |
31 | PC aa C42:2 | − 0.56 (− 0.72; − 0.40) | < .001 | − 0.61 (− 0.80; − 0.42) | < .001 | – | – |
32 | PC ae C32:1 | − 0.57 (− 0.78; − 0.37) | < .001 | − 0.9 (− 1.14; − 0.66) | < .001 | – | – |
33 | PC ae C34:2 | − 0.92 (− 1.14; − 0.71) | < .001 | − 1.24 (− 1.49; − 0.98) | < .001 | – | – |
34 | PC ae C36:2 | − 1.12 (− 1.35; − 0.90) | < .001 | − 1.32 (− 1.59; − 1.05) | < .001 | – | – |
35 | PC ae C36:3 | −0.87 (− 1.10; − 0.65) | < .001 | − 1.15 (− 1.42; − 0.88) | < .001 | – | – |
36 | PC ae C38:2 | − 1.05 (− 1.27; − 0.82) | < .001 | − 1.19 (− 1.46; − 0.92) | < .001 | – | – |
37 | PC ae C40:6 | − 0.89 (− 1.12; − 0.65) | < .001 | − 1.11 (− 1.38; − 0.83) | < .001 | – | – |
38 | PC ae C44:4 | − 1.05 (− 1.24; − 0.86) | < .001 | − 1.11 (− 1.34; − 0.89) | < .001 | – | – |
39 | SM C16:0 | − 0.58 (− 0.74; − 0.42) | < .001 | − 0.64 (− 0.83; − 0.45) | < .001 | – | – |
40 | PC ae C44:6 | − 0.64 (− 0.87; − 0.42) | < .001 | – | – | – | – |
41 | SM C18:1 | 0.49 (0.34; 0.64) | < .001 | – | – | – | – |
42 | Hexoses | 0.65 (0.44; 0.87) | < .001 | – | – | – | – |
43 | PC aa C32:2 | – | – | 0.45 (0.19; 0.72) | 0.002 | – | – |