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Fig. 3 | BMC Medicine

Fig. 3

From: Shared genetic etiology and causality between body fat percentage and cardiovascular diseases: a large-scale genome-wide cross-trait analysis

Fig. 3

The up and down plots display the MTAG and GWAS results for a BF%, b HF, and c CAD, respectively, for a fixed set of SNPs. The x axis shows chromosomal position, and the y axis shows significance on a −log10 scale. The line marks the threshold for genome-wide significance (P = 5 × 10− 8). Each approximately independent genome-wide significant association (lead SNP) is marked by a cross

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