Fig. 2

Serum CFP-10 can distinguish TB from unlikely TB cases and the comparison with other methods. a Serum CFP-10 signal in HIV-infected and HIV-uninfected children with TB and unlikely (UL) TB, where horizontal bars indicate mean values. ***p < 0.001 by ANOVA with Tukey’s post-test. b Venn diagram of all positive CFP-10pep, and Mtb culture and smear results. Note that one child diagnosed with unconfirmed TB subsequently had a positive Mtb culture, resulting in a mismatch between the overall number of confirmed TB cases and positive Mtb cultures. The positive proportions of culture, smear and CFP-10pep among extrapulmonary TB c PTB only and d EPTB cases