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Table 2 Summary of groups present in current study

From: Evaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study

 

Total * (N = 519)

HIV-infected (N = 284)

HIV-uninfected (N = 235)

P value

TB cases—no. (%)

117 (22.5)

66 (23.2)*

51 (21.7)

0.68

Confirmed PTB

6 (1.2)

3 (1.1)

3 (1.3)

0.26

Confirmed EPTB a

2 (0.4)

2 (0.7)

Unconfirmed PTB

108 (20.8)

60 (21.1)

48 (20.4)

  MTB infection b

73 (14.1)

45 (15.8)

28 (11.9)

0.10

  No MTB infection c

35 (6.7)

15 (5.3)

20 (8.5)

Unconfirmed EPTB d

3 (0.6)

3 (1.1)

Unlikely TBno. (%)

402 (77.5)

218 (76.8)

184 (78.3)

  MTB infection

53 (10.2)

32 (11.3)

21 (8.9)

0.33

  No MTB infection e

349 (67.3)

186 (65.5)

163 (69.4)

Died

9 (1.7)

7 (2.5)

2 (0.9)

0.16

  1. *Two infants diagnosed with both unconfirmed EPTB and unconfirmed PTB were counted once in this total
  2. aBoth of these EPTB cases were diagnosed as TB lymphadenitis
  3. bMTB infection = TST-positive (induration of ≥ 5 mm for HIV-infected infants and ≥ 10 mm for HIV-uninfected infants)
  4. cNo MTB infection = TST-negative (induration of < 5 mm for HIV-infected infants and < 10 mm for HIV-uninfected infants)
  5. dTwo infants were diagnosed with both unconfirmed TB lymphadenitis and unconfirmed PTB, and the third was diagnosed with TB meningitis
  6. eTST-negative or no TST result available for infants not suspected of TB who did not reach a protocol-designated visit for TST performance (parent study weeks 96, 144, 196)