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Table 2 Summary of groups present in current study

From: Evaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study

  Total * (N = 519) HIV-infected (N = 284) HIV-uninfected (N = 235) P value
TB cases—no. (%) 117 (22.5) 66 (23.2)* 51 (21.7) 0.68
Confirmed PTB 6 (1.2) 3 (1.1) 3 (1.3) 0.26
Confirmed EPTB a 2 (0.4) 2 (0.7)
Unconfirmed PTB 108 (20.8) 60 (21.1) 48 (20.4)
  MTB infection b 73 (14.1) 45 (15.8) 28 (11.9) 0.10
  No MTB infection c 35 (6.7) 15 (5.3) 20 (8.5)
Unconfirmed EPTB d 3 (0.6) 3 (1.1)
Unlikely TBno. (%) 402 (77.5) 218 (76.8) 184 (78.3)
  MTB infection 53 (10.2) 32 (11.3) 21 (8.9) 0.33
  No MTB infection e 349 (67.3) 186 (65.5) 163 (69.4)
Died 9 (1.7) 7 (2.5) 2 (0.9) 0.16
  1. *Two infants diagnosed with both unconfirmed EPTB and unconfirmed PTB were counted once in this total
  2. aBoth of these EPTB cases were diagnosed as TB lymphadenitis
  3. bMTB infection = TST-positive (induration of ≥ 5 mm for HIV-infected infants and ≥ 10 mm for HIV-uninfected infants)
  4. cNo MTB infection = TST-negative (induration of < 5 mm for HIV-infected infants and < 10 mm for HIV-uninfected infants)
  5. dTwo infants were diagnosed with both unconfirmed TB lymphadenitis and unconfirmed PTB, and the third was diagnosed with TB meningitis
  6. eTST-negative or no TST result available for infants not suspected of TB who did not reach a protocol-designated visit for TST performance (parent study weeks 96, 144, 196)