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Table 2 Association between qPCR-detectable P. falciparum or P. vivax infection and antibody response

From: Community-based molecular and serological surveillance of subclinical malaria in Myanmar

  Contemporaneous infection Infection at next presentation
aORa (95%CI) p value aORb (95%CI) p value
PfAMA1 IgG
 Seropositive 0.70 (0.52, 0.93) 0.01 0.98 (0.53, 1.80) 0.95
 Level (log2OD 450nm) 0.94 (0.84, 1.06) 0.34 0.91 (0.73, 1.10) 0.33
PfMSP2 IgG
 Seropositive 0.81 (0.61, 1.08) 0.15 1.27 (0.70, 2.29) 0.43
 Level (log2OD 450nm) 0.88 (0.80, 0.96) 0.005 0.92 (0.77, 1.11) 0.40
PfCSP IgG
 Seropositive 0.51 (0.35, 0.76) 0.001 0.29 (0.07, 1.21) 0.09
 Level (log2OD 450nm) 0.90 (0.83, 0.98) 0.02 1.02 (0.85, 1.24) 0.81
PvAMA1 IgGc
 Seropositive 1.02 (0.73, 1.43) 0.89
 Level (log2OD 450nm) 0.98 (0.86, 1.12) 0.75
  1. Adjusted for aage (years), sex, region, residential status, time (discrete month) and repellent distribution or bage (years), sex, region, residential status, time since the last measurement (days) and repellent distribution; conly contemporaneous IgG level/seropositivity exposures were estimated for P. vivax infections due to a small number of events for individuals with measurements performed on at least two occasions. Estimates for antigen- specific IgG seropositivity or level are derived from separate equations, (Additional File 2 Tables S3-S10)
  2. aOR adjusted odds ratio, 95%CI 95% confidence interval