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Table 1 The baseline characteristics of enrolled women

From: A randomized controlled trial of dihydroartemisinin-piperaquine, artesunate-mefloquine and extended artemether-lumefantrine treatments for malaria in pregnancy on the Thailand-Myanmar border

Baseline characteristic All (n = 511) DP (n = 172) ASMQ (n = 169) AL+ (n = 170)
EGA at first ANC (week)^ 15 [10–22] 15 [10–20] 15 [9–23.5] 15 [10–22.5]
EGA malaria (week)^ 26 [19–33] 25 [19–32] 27 [19–34] 26 [19–32]
Trimester
 1st 46 (9.0%) 13 (7.6%) 15 (8.9%) 18 (10.6%)
 2nd 236 (46.2%) 84 (48.8%) 74 (43.8%) 78 (45.9%)
 3rd 229 (44.8%) 75 (43.6%) 80 (47.3%) 74 (43.5%)
Age (years) 25.7 (6.8) 25.7 (6.8) 26.3 (6.7) 25.1 (7.0)
Gravidity
 1 171 (33.5%) 60 (34.9%) 46 (27.2%) 65 (38.2%)
 2 98 (19.2%) 30 (17.4%) 35 (20.7%) 33 (19.4%)
 ≥3 242 (47.4%) 82 (47.7%) 88 (52.1%) 72 (42.4%)
Parity
 0 204 (39.9%) 71 (41.3%) 57 (33.7%) 76 (44.7%)
 1 97 (19.0%) 36 (20.9%) 32 (18.9%) 29 (17.1%)
 ≥2 210 (41.1%) 65 (37.8%) 80 (47.3%) 65 (38.2%)
Smoking 101 (19.8%) 32 (18.6%) 34 (20.1%) 35 (20.6%)
Height (cm) 151.0 (5.4) 151.2 (5.3) 151.1 (5.5) 150.8 (5.5)
Weight (kg) 51.7 (7.6) 52.4 (8.3) 52.0 (7.4) 50.8 (7.0)
Fever (temperature ≥ 37.5) 146 (28.6%) 45 (26.2%) 48 (28.4%) 53 (31.2%)
Fever (including history of fever) 340 (66.5%) 115 (66.9%) 113 (66.9%) 112 (65.9%)
Haematocrit (%) 32.1 (4.0) 32.1 (4.1) 32.3 (4.1) 32.0 (3.9)
Anaemia
 No anaemia 406 (79.5%) 138 (80.2%) 135 (79.9%) 133 (78.2%)
 Moderate anaemia 105 (20.5%) 34 (19.8%) 34 (20.1%) 37 (21.8%)
 Severe anaemia 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
First recorded malaria in pregnancy 277 (78.5%) 89 (73.6%) 94 (83.9%) 94 (78.3%)
Species
 Pf mono-infection 142 (27.8%) 46 (26.7%) 52 (30.8%) 44 (25.9%)
 Pv mono-infection 353 (69.1%) 121 (70.3%) 112 (66.3%) 120 (70.6%)
 Pf and Pv coinfection 15 (2.9%) 4 (2.3%) 5 (3.0%) 6 (3.5%)
 Pm mono-infection 1 (0.2%) 1 (0.6%) 0 (0.0%) 0 (0.0%)
Pf parasitaemia (/uL)* 5689 (16–207994) 4561 (16–207994) 5805 (16–124595) 6936 (96–120199)
Pv parasitaemia (/uL)* 658 (16–83524) 674 (16–83524) 651 (16–29893) 648 (16–40694)
Presence of Pf gametocytes 24 (4.7%) 12 (7.0%) 6 (3.6%) 6 (3.5%)
Presence of Pv gametocytes 233 (45.6%) 81 (47.1%) 66 (39.1%) 86 (50.6%)
  1. AL+ artemether-lumefantrine extended regimen, ANC antenatal care, ASMQ artesunate-mefloquine, BMI body mass index, DP dihydroartemisinin-piperaquine, EGA estimated gestational age, Pf Plasmodium falciparum, Pm Plasmodium malariae, Pv Plasmodium vivaxSD standard deviation. Data are presented as mean (standard deviation), number (%), ^median [interquartile range] or *geometric mean (range)
  2. Anaemia was defined as a haematocrit of 20-29% (moderate) or less than 20% (severe)