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Table 1 Cohort participant characteristics and distribution of explanatory variables, by rotavirus vaccination status

From: Paediatric rotavirus vaccination, coeliac disease and type 1 diabetes in children: a population-based cohort study

Variable   Overall   No rotavirus vaccination Rotavirus vaccination P valuea
   N % n % n %  
Total participants   880,629   537,516   343,113   
Sex Male 450,956 51.2 275,336 51.2 175,620 51.2 0.719
  Female 429,673 48.8 262,180 48.8 167,493 48.8  
Year of birth 2010 162,510 18.5 161,049 30.0 1461 0.4 < 0.001
  2011 158,273 18.0 156,413 29.1 1860 0.5  
  2012 154,619 17.6 152,182 28.3 2437 0.7  
  2013 142,384 16.2 50,625 9.4 91,759 26.7  
  2014 135,007 15.3 9726 1.8 125,281 36.5  
  2015 127,836 14.5 7521 1.4 120,315 35.1  
Region North East 34,011 3.9 20,654 3.8 13,357 3.9 < 0.001
  North West 130,546 14.8 79,505 14.8 51,041 14.9  
  Yorkshire and Humber 31,402 3.6 19,359 3.6 12,043 3.5  
  East Midlands 21,895 2.5 13,548 2.5 8347 2.4  
  West Midlands 146,977 16.7 89,481 16.7 57,496 16.8  
  East of England 50,765 5.8 30,517 5.7 20,248 5.9  
  South West 110,315 12.5 67,537 12.6 42,778 12.5  
  South Central 109,198 12.4 66,514 12.4 42,684 12.4  
  London 180,914 20.6 111,218 20.7 69,696 20.3  
  South East Coast 64,231 7.3 38,920 7.2 25,311 7.4  
IMD quintile 1 173,439 19.7 104,602 19.5 68,837 20.1 < 0.001
  2 158,821 18.1 95,364 17.8 63,457 18.5  
  3 161,999 18.4 98,331 18.3 63,668 18.6  
  4 182,182 20.7 111,907 20.8 70,275 20.5  
  5 203,415 23.1 126,859 23.6 76,556 22.3  
T1D record No 879,896 99.9 537,027 99.9 342,869 99.9 0.001
  Yes 733 0.1 493 0.1 240 0.1  
CD record No 878,972 99.8 536,380 99.9 342,592 99.9 < 0.001
  Yes 1657 0.2 1136 0.2 521 0.2  
   Mean SD Mean SD Mean SD  
GP consultations per year   7.29 4.96 7.08 5.02 7.63 4.84 < 0.001
Person-days at-risk   1843 773 2015 809 1577 624 < 0.001
  1. SD standard deviation
  2. aComparing the distribution of participants within a variable between vaccinated and unvaccinated