|  | CD | T1D | ||||||
---|---|---|---|---|---|---|---|---|---|
Variable | Â | Univariable | Adjusted | Univariable | Adjusted | ||||
 |  | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI |
Rotavirus vaccination | No | ref | ref | ref | ref | ref | ref | ref | ref |
 | Yes | 0.93 | 0.84–1.04 | 1.05 | 0.86–1.28 | 1.01 | 0.87–1.19 | 0.89 | 0.68–1.19 |
Sex | Male | ref | ref | ref | ref | Ref | ref | ref | ref |
 | Female | 1.42 | 1.29–1.56 | 1.42 | 1.29–1.56 | 1.02 | 0.88–1.17 | 1.02 | 0.88–1.17 |
Year of birth | 2010 | ref | ref | ref | Ref | ref | ref | ref | ref |
 | 2011 | 0.98 | 0.85–1.14 | 0.98 | 0.85–1.14 | 1.08 | 0.86–1.34 | 1.08 | 0.86–1.34 |
 | 2012 | 1.03 | 0.89–1.19 | 1.03 | 0.89–1.19 | 0.93 | 0.74–1.17 | 0.93 | 0.74–1.17 |
 | 2013 | 0.91 | 0.77–1.06 | 0.88 | 0.72–1.08 | 1.11 | 0.88–1.41 | 1.19 | 0.89–1.58 |
 | 2014 | 0.95 | 0.80–1.13 | 0.91 | 0.71–1.17 | 1.15 | 0.90–1.48 | 1.28 | 0.89–1.82 |
 | 2015 | 0.84 | 0.70–1.02 | 0.81 | 0.6–1.02 | 0.89 | 0.65–1.19 | 0.98 | 0.66–1.46 |
Region | North East | ref | ref | ref | ref | Ref | Ref | ref | Ref |
 | North West | 1.18 | 0.85–1.63 | 1.12 | 0.82–1.54 | 0.81 | 0.55–1.18 | – | – |
 | Yorkshire and Humber | 1.45 | 0.97–2.15 | 1.39 | 0.95–2.04 | 0.61 | 0.35–1.06 | – | – |
 | East Midlands | 1.07 | 0.68–1.70 | 0.96 | 0.61–1.50 | 0.91 | 0.52–1.57 | – | – |
 | West Midlands | 1.18 | 0.86–1.62 | 1.10 | 0.80–1.51 | 0.66 | 0.45–0.97 | – | – |
 | East of England | 1.23 | 0.85–1.78 | 1.01 | 0.70–1.45 | 1.08 | 0.70–1.66 | – | – |
 | South West | 1.25 | 0.90–1.74 | 1.13 | 0.82–1.56 | 0.83 | 0.56–1.23 | – | – |
 | South Central | 1.40 | 1.01–1.94 | 1.14 | 0.83–1.58 | 0.77 | 0.52–1.15 | – | – |
 | London | 1.06 | 0.77–1.46 | 1.02 | 0.74–1.40 | 0.63 | 0.43–0.92 | – | – |
 | South East Coast | 1.31 | 0.93–1.86 | 1.11 | 0.79–1.57 | 0.94 | 0.62–1.43 | – | – |
IMD quintile | 1 | ref | ref | ref | ref | ref | Ref | ref | Ref |
 | 2 | 0.96 | 0.84–1.11 | 0.97 | 0.84–1.12 | 1.20 | 0.96–1.51 | 1.20 | 0.96–1.51 |
 | 3 | 0.86 | 0.75–1.00 | 0.87 | 0.75–1.02 | 1.05 | 0.83–1.33 | 1.05 | 0.83–1.33 |
 | 4 | 0.72 | 0.61–0.84 | 0.73 | 0.62–0.85 | 1.10 | 0.87–1.38 | 1.10 | 0.87–1.39 |
 | 5 | 0.58 | 0.50–0.68 | 0.58 | 0.49–0.69 | 1.02 | 0.81–1.29 | 1.02 | 0.81–1.29 |
GP consultations per year |  | 1.24 | 1.24–1.25 | – | – | 1.25 | 1.24–1.25 | – | – |