Table 3 Rate ratios for severe COVID-19 associated with risk conditions (with severe respiratory disease as reference category) in those eligible for shielding and not resident in care homes

Shielding eligibility category

Severe respiratory

3834 (49%)

744 (45%)

.

.

Solid organ transplant

112 (1%)

60 (4%)

1.58 (0.90, 2.77)

0.1

1.36 (0.70, 2.63)

0.4

Specific cancers

925 (12%)

240 (15%)

1.28 (0.98, 1.66)

0.07

0.88 (0.64, 1.21)

0.4

Rare diseases

348 (4%)

72 (4%)

1.18 (0.75, 1.84)

0.5

1.14 (0.68, 1.91)

0.6

On immunosuppressants

759 (10%)

129 (8%)

0.74 (0.53, 1.03)

0.07

0.82 (0.56, 1.20)

0.3

Additional conditions

1830 (23%)

395 (24%)

1.19 (0.95, 1.49)

0.1

1.00 (0.77, 1.31)

1

At least one child under 5

66 (1%)

27 (2%)

0.80 (0.32, 2.02)

0.6

0.45 (0.15, 1.31)

0.1

School-age children in household

0 school age

7537 (97%)

1545 (94%)

.

.

1 school age

82 (1%)

19 (1%)

0.36 (0.13, 0.99)

0.05

0.84 (0.29, 2.45)

0.7

2 or more

189 (2%)

76 (5%)

1.03 (0.60, 1.76)

0.9

0.74 (0.40, 1.37)

0.3

Adults in household

1 adult

5811 (75%)

1010 (62%)

.

.

2 adults

1647 (21%)

458 (28%)

1.60 (1.30, 1.97)

<0.001

1.74 (1.37, 2.21)

<0.001

3 or more

339 (4%)

167 (10%)

2.15 (1.51, 3.07)

<0.001

2.52 (1.66, 3.82)

<0.001

SIMD quintile (integer)

2 (1–4)

2 (1–4)

0.97 (0.91, 1.05)

0.5

0.98 (0.90, 1.06)

0.6

Recent hospital visit/stay

840 (11%)

739 (45%)

5.8 (4.6, 7.4)

<0.001

6.0 (4.7, 7.7)

<0.001