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Table 2 Main characteristics of HBV-infected babies in two different doses of HB vaccine

From: The effects of increased dose of hepatitis B vaccine on mother-to-child transmission and immune response for infants born to mothers with chronic hepatitis B infection: a prospective, multicenter, large-sample cohort study

Variables

10 μg (n = 5)

20 μg (n = 8)

At birth

 Sex (M)

4

2

 Gestation days

278.6 ± 3.5

277.5 ± 2.1

 Birth mode (vaginal delivery)

2

4

 Birth weight (g)

3480 ± 165.5

3300 ± 131.3

 Fetal distress

1

2

 1-min APGAR

9.6 ± 0.2

9.6 ± 0.18

At 12th month

 HBeAg +

5

5

 Anti-HBc

5

8

 HBV DNA detectable

3a

6b

 HBV DNA (log10 IU/mL)

6.7 ± 0.3

6.5 ± 0.2

  1. a10 μg: samples of 2 cases were unavailable
  2. b20 μg: 1 case HBV DNA < 100 IU/mL, samples of 2 cases were unavailable
  3. Abbreviations: HB hepatitis B, Anti-HBc antibody to hepatitis B c antigen, HBeAg hepatitis B e antigen, HBV hepatitis B virus