|
Screen positivity, n (%)
|
13 224 (4.0)
|
84 591 (10.1)
|
2.65 (2.59–2.70)
|
24 251 (10.0)
|
2.57 (2.52–2.63)
|
60 340 (10.2)
|
2.67 (2.62–2.72)
|
|
Per protocol colposcopy referral, n (%)a
|
13 224 (4.0)
|
29 032 (3.5)
|
0.85 (0.83–0.87)
|
5 256 (2.2)
|
0.51 (0.49–0.52)
|
23 776 (4.0)
|
0.98 (0.96–1.00)
|
|
Overall colposcopy referral, n (%)
|
12 312 (4.4)
|
33 067 (4.5)
|
1.03 (1.00–1.05)
|
7 395 (3.3)
|
0.76 (0.74–0.78)
|
25 672 (5.0)
|
1.13 (1.10–1.15)
|
|
Per protocol detection rate of CIN or cancer, n (per 1000)
|
|
CIN2+
|
1222 (4.4)
|
3860 (5.5)
|
1.18 (1.11–1.25)
|
962 (4.4)
|
0.92 (0.85–1.00)
|
2898 (5.9)
|
1.28 (1.20–1.36)
|
|
CIN2 or 3
|
1125 (4.0)
|
3523 (5.0)
|
1.17 (1.09–1.24)
|
859 (4.0)
|
0.89 (0.82–0.97)
|
2664 (5.4)
|
1.28 (1.20–1.36)
|
|
Invasive cervical cancer
|
97 (0.3)
|
337 (0.5)
|
1.33 (1.08–1.64)
|
103 (0.5)
|
1.31 (1.00–1.70)
|
234 (0.5)
|
1.34 (1.07–1.66)
|
|
Overall detection rate of CIN or cancer, n (per 1000) b
|
|
CIN2+
|
1302 (4.6)
|
4099 (5.7)
|
1.17 (1.10–1.24)
|
1076 (4.9)
|
0.96 (0.88–1.03)
|
3023 (6.1)
|
1.26 (1.18–1.33)
|
|
CIN2 or 3
|
1171 (4.2)
|
3698 (5.2)
|
1.17 (1.09–1.24)
|
945 (4.3)
|
0.93 (0.85–1.01)
|
2753 (5.6)
|
1.27 (1.19–1.35)
|
|
Invasive cervical cancer
|
131 (0.5)
|
401 (0.6)
|
1.18 (0.98–1.43)
|
131 (0.6)
|
1.23 (0.97–1.56)
|
270 (0.5)
|
1.16 (0.95–1.41)
|
|
Positive predictive value, n (%) c
|
|
CIN2+
|
1222 (10.9)
|
4030 (13.8)
|
1.29 (1.21–1.37)
|
1045 (16.8)
|
1.60 (1.47–1.75)
|
2985 (13.0)
|
1.22 (1.14–1.30)
|
|
CIN2 or 3
|
1125 (10.0)
|
3668 (12.6)
|
1.27 (1.19–1.36)
|
926 (14.9)
|
1.52 (1.39–1.66)
|
2742 (12.0)
|
1.21 (1.13–1.30)
|
|
Invasive cervical cancer
|
97 (0.9)
|
362 (1.2)
|
1.42 (1.16–1.75)
|
119 (1.9)
|
2.20 (1.70–2.85)
|
243 (1.1)
|
1.24 (0.99–1.54)
|
