From: Salivary metabolites associated with a 5-year tooth loss identified in a population-based setting
 | PheWAS variable | 2-Pyrrolidineacetic acid | X-23662 | Butyrylputrescine | N,N-dimethyl-5-aminovalerate | N-acetyl-cadaverine | N6,N6,N6-trimethyllysine | N-acetyltaurine | Phenylacetate | Dimethylarginine (SDMA + ADMA) |
---|---|---|---|---|---|---|---|---|---|---|
Smoking | Smoking (current) | + 0.0001 | + 0.031 | + 0.00013 | + 0.0011 | + 0.047 | Â | - 0.020 | Â | Â |
Cardio-metabolic disorders | Known or diagnosed diabetes mellitus | Â | + 0.030 | Â | Â | Â | Â | Â | Â | Â |
Known diabetes mellitus | Â | + 0.023 | Â | Â | Â | Â | Â | Â | Â | |
Diagnosed high blood pressure | Â | + 0.026 | Â | Â | Â | Â | Â | Â | Â | |
Systolic blood pressure (mmHg) | Â | + 0.026 | Â | Â | + 0.034 | + 0.023 | Â | Â | Â | |
Triglycerides (total) (mmol/l) | Â | Â | Â | Â | Â | Â | - 0.020 | Â | Â | |
Inflammation | Fibrinogen acc. to Clauss (g/l) | Â | Â | + 0.026 | Â | Â | + 0.023 | Â | Â | + 0.019 |
Leukocytes (Gpt/l) | + 0.03 | + 0.0003 | + 0.00044 | Â | + 0.000004 | + 0.021 | Â | Â | + 0.002 | |
Mean corpuscular haemoglobin (mmol/l) | Â | - 0.023 | Â | Â | - 0.015 | Â | Â | Â | Â | |
Red cell distribution width (%) | Â | Â | Â | Â | Â | Â | Â | Â | + 0.019 | |
Obesity | Weight (kg) | Â | + 0.003 | Â | Â | + 0.002 | + 0.015 | Â | Â | Â |
Waist circumference (cm) | Â | + 0.0003 | Â | Â | + 0.0006 | + 0.023 | Â | + 0.032 | + 0.019 | |
Hip circumference (cm) | Â | + 0.0067 | Â | Â | + 0.005 | + 0.032 | Â | Â | + 0.047 | |
Others | Bad breath | Â | Â | + 0.033 | Â | Â | Â | Â | Â | Â |
Sodium (mmol/l) | Â | Â | + 0.029 | Â | Â | Â | Â | Â | Â | |
Serum amylase (μkatal/l) |  |  |  |  |  | - 0.023 |  |  |  |