AF cases, n = 1,920 | CVD death (n = 599) | Non-CVD death (n = 722) | ||
---|---|---|---|---|
sHR | P value | sHR | P value | |
Age at diagnosis, years | 6.33 (5.44, 7.37) | < 0.001 | 7.61 (6.54, 8.86) | < 0.001 |
Female | 0.96 (0.80, 1.14) | 0.60 | 1.06 (0.91, 1.25) | 0.44 |
Systolic BP, mmHg | 1.24 (0.81, 1.88) | 0.32 | 0.91 (0.75, 1.10) | 0.32 |
Diastolic BP, mmHg | 1.05 (0.95, 1.16) | 0.32 | 1.05 (0.95, 1.16) | 0.32 |
Body mass index, kg/m2 | 0.98 (0.90, 1.08) | 0.71 | 0.94 (0.86, 1.02) | 0.14 |
Current smoker | 0.95 (0.74, 1.22) | 0.67 | 1.37 (1.11, 1.69) | 0.004 |
Elevated alcohol consumption | 0.86 (0.70, 1.06) | 0.16 | 1.06 (0.88, 1.27) | 0.55 |
Diabetes | 1.18 (0.93, 1.48) | 0.17 | 0.88 (0.70, 1.10) | 0.26 |
Hypertension treatment | 1.18 (0.99, 1.41) | 0.06 | 0.86 (0.74, 1.01) | 0.06 |
Prior heart failure | 1.49 (1.14, 1.94) | 0.003 | 0.70 (0.51, 0.96) | 0.02 |
Prior myocardial infarction | 1.44 (1.15, 1.80) | 0.002 | 0.89 (0.71, 1.12) | 0.32 |
Prior stroke or transient ischemic attack | 1.27 (0.99, 1.64) | 0.06 | 0.96 (0.75, 1.23) | 0.75 |
Prior cancer | 0.56 (0.46, 0.70) | < 0.001 | 1.94 (1.65, 2.28) | < 0.001 |
Secondary AF | 0.92 (0.78, 1.10) | 0.36 | 1.42 (1.22, 1.66) | < 0.001 |
Anticoagulation at diagnosis | 1.00 (0.80, 1.24) | 0.98 | 0.88 (0.72, 1.07) | 0.20 |
Antiplatelet therapy at diagnosis | 0.71 (0.57, 0.88) | 0.002 | 0.99 (0.82, 1.18) | 0.88 |
Epoch | Â | Â | Â | Â |
 1990–2002 vs. < 1990 | 0.69 (0.56, 0.85) | < 0.001 | 1.22 (1.01, 1.47) | 0.04 |
 ≥ 2003 vs. < 1990 | 0.74 (0.57, 0.97) | 0.03 | 1.18 (0.92, 1.52) | 0.18 |