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Table 2 Characteristics of 14 studies included in meta-analyses

From: Association of alcohol consumption with morbidity and mortality in patients with cardiovascular disease: original data and meta-analysis of 48,423 men and women

Source Country Dataset Sex Study size, No. Meta-analyses Inclusiona Follow up, yb Baseline age, yc Reference group including former drinkers Pre-/post-event alcohol assessment Multiple alcohol measures Quality assessment score Primary event
ACM case, No. CVM case, No. CVE case, No.
HSE/SHeSs UK HSE (1994–2008) / SHeSs (1995, 1998, 2003) M, F 2802 1257 492 NA 9.5 67.3 Bothd Post- No 9 MI/angina, strokee
UK Biobank UK Initial assessment visit (2006–2010) M, F 14,386 1640 631 2950 8.7 61.6 Bothd Post- No 9 MI, angina, stroke
Levantesi et al., 2013 [12] Italy GISSI study M, F 11,248 1656 NA 1168 5.7 59.4 Yes Post- Yes 7 MI
Pai et al., 2012 [13] USA Health Professionals Follow-up Study M 1818 468 243 NA Up to 20 Range
40–75
Yes Both Yes 7 MI
Rosenbloom et al., 2012 [14] USA Onset study F 1253 441 NA NA Up to 10 66.1 Yes Pre- No 9 MI
Janszky et al., 2008 [44] Sweden SHEEP study M, F 1332 259 140 NA 8.6 59.4 No Pre- No 9 MI
Masunaga et al., 2006 [41] Japan Consecutive patients M 3845 NA NA 142 1.1 57.2 No Post- No 8 MI
Aguilar et al., 2004 [36] USA, Canada SAVE trial M, F 2036 355 284 NA 3.5 59.2 Yes Both No 7 MI
Jackson et al., 2003 [37] USA Physicians’ Health Study M 1320 369 267 NA 4.5 67.4 Yes Post- No 6 Stroke
de Lorgeril et al., 2002 [43] France Lyon Diet Heart Study M 353 NA NA 104 4.0 54.0 Yes Post- Yes 7 MI
Mukamal et al., 2001 [45] USA Onset study M, F 1913 317 238 NA 3.8 61.8 Yes Pre- No 8 MI
Shaper et al., 2000 [46] UK British Regional Heart Study M 596 258 184 NA 12.8 Range
45–64
No Post- No 9 MI, angina
Valmadrid et al., 1999 [56] USA WESDR M, F 163 NA 52 NA Up to 12.3 68.6 No Post- No 9 MI/anginae, f
Muntwyler et al., 1998 [38] USA Physicians’ Health Study M 5358 920 NA NA 5.0 64.1 Yes Post- No 6 MI
  1. ACM all-cause mortality, CVE cardiovascular events, CVM cardiovascular mortality, F female, HSE the Health Survey for England, M male, MI myocardial infarction, SHeSs the Scottish Health Survey
  2. aNot applicable (NA) if the study was not included in meta-analysis on the outcome
  3. bData are mean/median unless otherwise specified
  4. cData are mean unless otherwise specified
  5. dFormer drinkers were included only in subgroup meta-analyses on different non-drinking reference group
  6. eResults were not reported separately for angina and MI patients
  7. fOlder-onset diabetic patients with a history of angina or MI