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Table 1 Prevalence and results from Cox regressions of any mental health outcomes (excluding developmental delay). Univariable, sociodemographic and perinatal only (Model 1) and including ACEs (Model 2)

From: Adverse childhood experiences and child mental health: an electronic birth cohort study

Any mental health diagnoses or symptoms (excluding developmental delay) (HR 95% CI)

 

Prevalence for those diagnosed (n = 3571)

Univariable

Social deprivation, demographic and perinatal variables

ACEs adjusted for demographic and perinatal variables

Ever any household member with an alcohol-related hospital admission

 No

2848 (79.8%)

1.00 (ref)

-

1.00 (ref)

 Yes

723 (20.3%)

1.41 (1.27–1.56)

-

1.10 (0.99–1.23)

Ever death of any household member

 No

~3571 (100%)

1.00 (ref)

-

1.00 (ref)

 Yes

<5

1.01 (0.73–1.39)

-

0.92 (0.67–1.27)

Household member ever had a common mental health disorder or psychosis GP code

 No

1232 (34.5%)

1.00 (ref)

-

1.00 (ref)

 Yes

2339 (65.5%)

1.74 (1.63–1.87)

-

1.63 (1.52–1.75)

Household member ever had a serious mental illness GP code

 No

3478 (97.4%)

1.00 (ref)

-

1.00 (ref)

 Yes

93 (2.6%)

1.77 (1.30–2.41)

-

1.35 (0.99–1.84)

Any childhood victimisation hospital admission

 No

3471 (97.2%)

1.00 (ref)

-

1.00 (ref)

 Yes

100 (2.8%)

2.40 (1.69–3.40)

-

1.90 (1.34–2.69)

Ever in a single parent household

 No

2054 (57.5%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Yes

1517 (42.5%)

1.13 (1.04–1.22)

1.00 (0.92–1.08)

1.03 (0.95–1.11)

Townsend deprivation quintile at birth or in first 4 months (0.4% missing data)

 1 (least deprived)

494 (13.8%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 2

590 (16.5%)

1.18 (1.04–1.34)

1.13 (0.99 - 1.28)

1.12 (0.99–1.27)

 3

675 (18.9%)

1.29 (1.15–1.46)

1.17 (1.03–1.32)

1.14 (1.01–1.29)

 4

772 (21.6%)

1.42 (1.26–1.60)

1.23 (1.09–1.40)

1.19 (1.05–1.35)

 5 (most deprived)

1027 (28.8%)

1.63 (1.46–1.83)

1.32 (1.16–1.51)

1.26 (1.11–1.43)

Sex

 Male

2059 (57.7%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Female

1512 (42.3%)

0.78 (0.73–0.84)

0.79 (0.73–0.84)

0.79 (0.74–0.85)

Breastfeeding at birth or 6-8 weeks (20.8% missing data)

 No

1490 (41.7%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Yes

1338 (37.5%)

0.78 (0.72–0.85)

0.88 (0.81–0.96)

0.90 (0.82–0.98)

Maternal age at birth or at 6-8 weeks (<5 missing)

 30–34 years

12%

0.84 (0.76–0.92)

0.89 (0.80–0.98)

0.91 (0.82–1.01)

 ≥35 years

23%

0.80 (0.72–0.91)

0.87 (0.77–0.99)

0.89 (0.78–1.00)

 25–29 years

28%

1.00 (ref)

1.00 (ref)

1.00 (ref)

 <18 years

3%

1.37 (1.12–1.69)

1.14 (0.92–1.42)

1.09 (0.88–1.36)

 18–24 years

34%

1.40 (1.28–1.53)

1.27 (1.15–1.39)

1.22 (1.11–1.35)

Gestational age at birth (4.2% missing data)

 24≤28 weeks

11 (0.3%)

1.15 (0.60–2.22)

1.07 (0.55–2.07)

1.03 (0.53–1.99)

 28≤33 weeks

47 (1.3%)

1.13 (0.84–1.52)

1.09 (0.81–1.48)

1.05 (0.74–1.43)

 33≤37 weeks

246 (6.9%)

1.24 (1.08–1.43)

1.24 (1.06–1.44)

1.22 (1.05–1.42)

 37–43 weeks

3116 (87.3%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

Parity (0.2% missing data)

 0

1671 (46.8%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 ≥1

1892 (53.0%)

0.84 (0.79–0.91)

0.90 (0.84–0.98)

0.88 (0.82–0.95)

Multiple births

 No

3480 (97.5%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Yes

91 (2.5%)

0.83 (0.66–1.03)

0.79 (0.63–1.00)

0.80 (0.64–1.01)

Small for gestational age (<10th centile) (4.9% missing data)

 No

3027 (84.8%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Yes

369 (10.3%)

1.21 (1.08–1.36)

1.11 (0.99–1.25)

1.10 (0.97–1.24)

Congenital anomalies

 None

3341 (93.6%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Minor

27 (0.8%)

1.02 (0.68–1.53)

0.96 (0.64–1.45)

0.95 (0.63–1.44)

 Major

203 (5.7%)

1.55 (1.34–1.80)

1.51 (1.30–1.75)

1.50 (1.29–1.74)

Maternal cigarette smoking at booking in (71.3% missing data)

 No

739 (20.7%)

1.00 (ref)

1.00 (ref)

1.00 (ref)

 Yes

285 (8.0%)

1.41 (1.08–1.84)

1.20 (0.89–1.63)

1.19 (0.88–1.60)