Fig. 5

The comparison of the prognostic model with the ELN system and other models. A, B In GSE6891 (n=291) and the TCGA database (n=173), AML patients in the high-score group had worse prognostic survival than those in the low-score group (both P < 0.001). C, D The model divided the IR-AML patients into two groups with significant differences in survival (both P < 0.001) in GSE6891 (n=175) and the TCGA database (n = 92). In GSE6891 and the TCGA database, E, F compared with LSC17, Yang, Wang’ models, and ELN system, the 121-gene prognostic model had the highest AUC value of survival ROC. G, H The 121-gene prognostic model had a higher C-Index value than the LSC17, Yang, Wang’ models, and the ELN system. IR-AML, intermediate-risk AML; AUC, area under the curve; ROC, receiver operating characteristic; C-index, concordance index