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Table 1 Clinical characteristics of the patients

From: One-year follow-up of chest CT findings in patients after SARS-CoV-2 infection

 

All (n = 41)

Mild patients (n = 25)

Severe patients (n = 16)

p value

Age, years

51 (38, 59)

48 (38, 58)

51.5 (37, 60.5)

0.698

Male, n (%)

24 (58.5%)

11 (44%)

13 (81.2%)

0.018

BMI, kg/m2

24.2 (21.9, 25.1)

24.2 (21.9, 25.1)

24.0 (22.2, 25.8)

0.873

Smoking history

4 (9.76%)

2 (8%)

2 (12.5%)

0.636

Comorbidities

    

 Hypertension, n (%)

10 (24.4%)

4 (16%)

6 (37.5%)

0.118

 Type 2 diabetes, n (%)

4 (9.7%)

2 (8%)

2 (12.5%)

0.636

 Coronary artery heart disease, n (%)

2 (4.9%)

1 (4%)

1 (6.25%)

0.745

 COPD/emphysema, n (%)

2 (4.9%)

2 (8%)

0 (0%)

0.246

Illness progress

    

 Duration from illness onset to hospital admission, days

5 (2, 7)

6 (4, 8)

5 (1.5, 6)

0.427

 Nasopharyngeal viral RNA shedding duration, days

19 (15, 26)

17 (13, 23)

22 (16, 28)

0.077

 Duration of hospitalization, days

17 (14, 23)

16 (12, 19)

19 (15.5, 25.5)

0.071

 ICU admission, n (%)

3 (7.3%)

0 (0%)

3 (18.7%)

0.024

 HFNC, n (%)

6 (14.6%)

0 (0%)

6 (37.5%)

0.001

 Corticosteroid treatment, n (%)

30 (73.2%)

15 (60%)

15 (93.75%)

0.017

 Median corticosteroid dose

60 (40,80)

40 (40, 60)

80 (40,80)

0.112

PFTs at 1-year follow-up#

    

 DLCO < 80%, n (%)

3 (7.3%)

1 (4.0%)

2 (12.5%)

0.515

 TLC < 80%, n (%)

5 (12.2%)

2 (8%)

3 (18.7%)

0.538

 FEV1/FVC < 0.70, n (%)

3 (7.3%)

3 (12.0%)

0 (0%)

0.087

 FVC %

97 (86, 105)

99 (93, 106)

91.5 (81, 103.5)

0.25

 FEV1 %

100 (87, 104)

100 (91, 104)

95.5 (80, 104.5)

0.399

 PEF

88 (71, 100)

92 (69, 100)

82.5 (71, 96.5)

0.584

 FEV1/FVC

82.4 (78.3, 85.1)

83 (77.9, 85)

81.45 (78.3, 85.6)

0.947

 DLCO %

112 (99, 121)

113 (106, 122)

101 (91.5, 120)

0.067

 TLC %

96 (88, 107)

99 (94, 110)

92.5 (86, 104)

0.057

 RV %

120 (106, 132)

131 (110, 144)

109.5 (105.5, 120.5)

0.014

  1. The quantitative data are shown as median data and inter quartile range data in brackets
  2. The occurrence data are shown as no. (%). Values indicate no. of positive results/total no. of patients with available assay results
  3. Kruskal-Wallis test for continuous variables or Fisher’s exact test for categorical variables was used for comparison between groups when applicable with p < 0.05 as significant
  4. Abbreviations: BMI, body mass index; ICU, intensive care unit; HFNC, high flow nasal catheter oxygen therapy; PFTs, pulmonary function tests; FVC, forced vital capacity; FEV1, forced expiratory volume in the first 1 s of expiration; PEF, peak expiratory flow; DLCO, diffusing capacity of the lung for carbon monoxide; TLC, total lung capacity; RV, residual volume
  5. #Pulmonary function tests were expressed as percent of the predicted value