Fig. 4

Number of nosocomial transmissions of the SARS-CoV-2 variant for each simulation scenario. Results shown are based on R_S = 1.95 and R_A = 0.8 (reproduction numbers for the SARS-CoV-2 variant with 56% higher transmissibility with respect to the wild-type SARS-CoV-2 variant). Summary statistics were calculated for 100 simulations. The full rectangular bar height represents the mean total number of nosocomial transmissions during the whole study period. The grey error bars represent the corresponding 95% uncertainty intervals. Patients that acquire a SARS-CoV-2 nosocomial infection may be diagnosed in the hospital (due to symptom onset during hospital stay or due to detection by an intervention) or discharged to the community in a pre-symptomatic or asymptomatic state. The rectangular bars with the black border represent the mean number of individuals (patients and HCWs) infected with SARS-CoV-2 and diagnosed in the hospital. The lighter rectangular bars represent the remaining mean number of patients discharged to community undiagnosed. For screening every 3 days and 7-day contact tracing, we considered two different test sensitivity scenarios: time-invariant perfect test sensitivity (perfect sens) and time-varying imperfect test sensitivity.