Table 1 Study population characteristics by P. falciparum infection at enrolment
Variable | Total (N=302) | Uninfected at enrolment (N=199) | Infected at enrolment (N=103) |
|---|---|---|---|
Enrolment demographics | |||
 Age | 24 (21–28) | 24 (21–30) | 23 (20–27) |
 Gestational age (weeks) | 26 (22–28) | 26 (22–28) | 25 (22–29) |
 Gravidity | |||
  Primigravid | 115/302 (38%) | 66/199 (33%) | 49/103 (48%) |
  Multigravid | 187/302 (62%) | 133/199 (67%) | 54/103 (52%) |
 Middle upper arm circumference | 22 (21–23) | 23 (21–24) | 22 (22–23) |
 Smokes | 60/301 (20%) | 40/199 (20%) | 20/2102 (20%) |
Infections at enrolment | |||
 Peripheral P. falciparuma | 103/302 (34%) | 0/199 (0%) | 103/103 (100%) |
Infections at delivery | |||
 Peripheral P. falciparuma | 32/288 (11%) | 22 /190 (12%) | 11/98 (11%) |
Placental histologyb | |||
 No infection | 81/233 (35%) | 64/154 (41) | 17/79 (21%) |
 Acute infection | 90/233 (39%) | 64/154 (39%) | 30/79 (38%) |
 Chronic infection | 42/233 (18%) | 21/154 (14%) | 21/79 (27%) |
 Past infection | 20/233 (8%) | 9/154 (6%) | 11/79 (14%) |
Hemoglobin at delivery | |||
 Hemoglobin (g/dl) | 9.4 (8.2–10.3) | 9.4 (8.2–10.5) | 9.2 (8.2–10.2) |
 Severe anemia (<8g/dl) | 68/285 (24%) | 45/188 (24%) | 23/97 (24%) |
Residence | |||
 Town | 7/299 (2%) | 7/197 (4%) | 0/102 (0%) |
 Village | 292/299 (98%) | 190/197 (96%) | 102/102 (100%) |
Maternal Genetics | |||
SAO | |||
 Normal | 261/302 (86%) | 176/199 (88%) | 85/103 (83%) |
 SAO | 41/302 (14%) | 23/199 (12%) | 18/103 (17%) |
α+thalassaemia | |||
 Normal α globin | 59/302 (20%) | 40/199 (20%) | 19/103 (19%) |
 Heterozygous | 112/302 (43%) | 72/199 (36%) | 40/103 (39%) |
 Homozygous | 131/302 (37%) | 87/199 (44%) | 44/103 (43%) |