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Table 1 Patient and tumour characteristics of TNBC

From: Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer

Baseline characteristics (n = 83)

N (% or range)

Age (mean)

52 (29–78)

AJCC stage

 Stage I, stage IA

18 (21.7)

 Stage IIA, stage IIB

52 (62.7)

 Stage IIIA, stage IIIB, stage IIIC

12 (14.5)

PAM50 subtype

 Basal

64 (80.7)

 Her2

5 (6.0)

 LumB

1 (1.2)

HRD status

 HR deficiency

48 (57.8)

 HR proficiency

35 (42.2)

BRCA1/2 mutation

 BRCA1

6 (7.2)

 BRCA2

5 (6.0)

BRCA1 promoter methylation

7 (7.2)

ACT chemotherapy response

 Complete response

21 (25.3)

 Partial response

2 (2.4)

 Progressive disease

1 (1.2)

 –

59 (71.1)

ACT response status

 Sensitive

39 (47.0)

 Resistant

44 (53.0)