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Fig. 1 | BMC Medicine

Fig. 1

From: Absolute quantitative proteomics using the total protein approach to identify novel clinical immunohistochemical markers in renal neoplasms

Fig. 1

Statistical analysis of renal tissue proteome data. A Pearson correlation coefficients between biological and technical replicates for each tumor subtype and the normal adjacent tissue (NAT) control. For example, 1.1 and 1.2 correspond to sample 1 replicate 1 and replicate 2, respectively. B Numbers of proteins identified for each tumor subtype and NAT. C Principal component analysis using the set of 1234 proteins selected for quantification (see text for details). D Distribution of TPA-based protein concentrations (pmol of protein per mg of total protein) highlighting proteins described in the literature as potential ccRCC markers (red dots, proteins are listed in additional file 6: Table S5). Subtypes: ccRCC, clear cell renal cell carcinoma; pRCC, papillary renal cell carcinoma; chRCC, chromophobe renal cell carcinoma; RO, renal oncocytoma

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