Table 1 Model parameters used in the base case and one-way sensitivity analyses
From: SARS-CoV-2 infection risk during delivery of childhood vaccination campaigns: a modelling study
Parameter | Description | Base case | Sensitivity analysis | Source |
|---|---|---|---|---|
R0 | Basic reproduction number | 2.0 | 1.8, 2.2 | Assumed |
Age-specific contact matrices | See Additional file 1: Fig S2. | 17 | ||
Reduction in contacts outside of home due to NPIs | 40% | 20%, 60% (30%, 20%)a | Assumed | |
| Susceptibility to infection on contact | Derived from R0 as described in Davies et al. | 14 | |
de | Latent period (pre-infectious) | 4 days | 2 days, 6 days | 14 |
dr | Duration of infectiousness | 5 days | 3 days, 7 days | 14 |
dc | Duration of the vaccination campaign | 10 days | 5 days, 20 daysb | Expert opinion + 8,23 |
| Number of children vaccinated by a vaccinator per day | Fixed-post: 150 House-to-house: 75 | Fixed-post: 75, 300 House-to-house: not varied | Expert opinion + 8,23,24 |
ncj | Number of community contacts of children/caregiver during trip to/from vaccine clinic | Fixed-post: 5 House-to-house: 0 | Fixed-post: 1, 10 House-to-house: not varied | Assumed |
| Number of vaccination staff contacted by children/caregivers during vaccination | 1 | 3 | Expert opinion + 26 |
| Number of extra community contacts of vaccinators for each household visited during the campaign | Fixed-post: 0 House-to-house: 1 | House-to-house: 0, 2 | Assumed |
π | Effectiveness of PPE in reducing transmission | 75% | 0%, 50%, 90%, 100% | 22,27 |
ρ | Relative effectiveness of PPE in reducing transmission to vaccinators or vaccinees/caregivers | 1 | 0.5 for vaccinators, 0.5 for caregivers | Assumed |
