Table 1 Clinical characteristics of enrolled subjects
From: HBeAg mediates inflammatory functions of macrophages by TLR2 contributing to hepatic fibrosis
Variable | CHB (n = 151) | AHB (n = 61) | P |
|---|---|---|---|
Age (years) | 54.41±9.69 | 36.54±11.79 | <0.001 |
Sex (male) | 121 (80.10%) | 45 (73.80%) | 0.309 |
ALT (IU/L) | 36.00 (25.00, 49.00) | 1325.00 (774.70, 2345.50) | <0.001 |
AST (IU/L) | 32.00 (20.00, 50.00) | 897.00 (375.00, 1351.50) | <0.001 |
HBeAg (COI) | 0.14 (0.11, 1.20) | 20.03 (5.85, 148.88) | <0.001 |
HBsAg (COI) | 5611.50 (879.15, 6902.00) | 3666.61 (1381.50, 5918.0) | 0.426 |
HBV DNA (log10 IU/mL) | 3.27±1.83 | 4.61±1.34 | <0.001 |
Stage of fibrosis | Â | NS | NS |
 0 | 13 (8.61%) |  |  |
 1 | 14 (9.27%) |  |  |
 2 | 44 (29.14%) |  |  |
 3 | 20 (13.25%) |  |  |
 4 | 60 (39.73%) |  |  |
Grade of inflammation | Â | NS | NS |
 0 | 10 (6.62%) |  |  |
 1 | 92 (60.93%) |  |  |
 2 | 29 (19.21%) |  |  |
 3 | 20 (13.25%) |  |  |