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Table 1 Patient characteristics by multimorbidity class

From: Association of multimorbidity and changes in health-related quality of life following myocardial infarction: a UK multicentre longitudinal patient-reported outcomes study

Variable

Total cohort

n=9566

Multimorbidity class 1 (severe) 591 (6.5%)

Multimorbidity class 2 (moderate) 4301 (47.6%)

Multimorbidity class 3 (mild) 4147 (45.9%)

P value†

Age, mean (SD)

64.1 (11.9)

74.8 (9.3)

68.8 (10.3)

57.7 (10.5)

<0.001*

Women, n (%)

2384 (24.9)

177 (30.0)

1274 (29.7)

803 (19.4)

<0.001*

IMD, mean (SD)

23.0 (15.7)

24.0 (16.2)

22.3 (15.2)

23.7 (16.1)

0.04

BMI, mean(SD)

28.7 (6.0)

29.8 (5.4)

28.9 (5.5)

28.2 (6.5)

<0.001*

Ethnicity (Caucasian), n (%)

8136 (85.1)

507 (94.8)

3639 (94.2)

3530 (93.3)

0.41

Ex/current smoking status, n (%)

6248 (65.3)

368 (64.6)

2709 (64.2)

5979 (67.2)

<0.001*

NSTEMI, n (%)

5658 (59.2)

508 (86.0)

2870 (66.7)

2046 (49.3)

<0.001*

STEMI, n (%)

3908 (40.8)

83 (14.0)

1431 (33.3)

2101 (50.7)

 

Co-morbidities

     

Diabetes, n (%)

1714 (17.9)

375 (64.7)

1143 (27.1)

107 (2.6)

<0.001*

Peripheral vascular disease, n (%)

317 (3.3)

121 (20.5)

168 (3.9)

24 (0.6)

<0.001*

Cerebrovascular disease, n (%)

428 (4.5)

122 (20.6)

297 (6.9)

0

<0.001*

Asthma or COPD, n (%)

1166 (12.2)

147 (24.9)

651 (15.1)

358 (8.6)

<0.001*

Chronic renal failure, n (%)

289 (3.0)

235 (39.8)

45 (1.1)

8 (0.2)

<0.001*

Heart failure, n (%)

212 (2.2)

203 (34.4)

0

6 (0.1)

<0.001*

Hypertension, n (%)

4078 (42.6)

408 (69.0)

3295 (76.6)

337 (8.1)

<0.001*

Previous MI, n (%)

1522 (15.9)

384 (65.0)

1006 (23.4)

114 (2.8)

<0.001*

Angina, n (%)

1792 (18.7)

374 (63.3)

1322 (30.7)

80 (1.9)

<0.001*

Previous PCI, n (%)

899 (9.4)

169 (28.7)

617 (14.4)

98 (2.4)

<0.001*

CABG surgery, n (%)

643 (6.7)

152 (25.8)

452 (10.5)

29 (0.7)

<0.001*

Discharge medications

     

Aspirin, n (%)

8147 (85.2)

464 (79.2)

3626 (84.7)

3636 (87.9)

<0.001*

ACE inhibitors, n (%)

7609 (79.5)

418 (71.3)

3389 (79.2)

3436 (83.1)

<0.001*

Beta-blockers, n (%)

7592 (79.7)

430 (73.4)

3340 (78. 0)

3439 (83.1)

<0.001*

Statin, n (%)

8140 (85.1)

477 (81.4)

3619 (84.6)

3636 (87.9)

<0.001*

Rehabilitation

     

Cardiac rehabilitation, n (%)

8509 (88.9)

502 (85.1)

3854 (90.3)

3877 (94.5)

<0.001*

  1. IMD Index of Multiple Deprivation, BMI body mass index, ACE angiotensin-converting enzyme, STEMI ST-elevation myocardial infarction, NSTEMI non-STEMI, CABG coronary artery bypass grafting, PCI percutaneous coronary intervention, AMI acute myocardial infarction, COPD Chronic Obstructive Pulmonary Disease. †Obtained from chi-squared or analysis of variance (ANOVA) as appropriate. *Significant after Hochberg correction using a false discovery rate of 0.05