Fig. 2From: Discovery and validation of methylation signatures in circulating cell-free DNA for early detection of esophageal cancer: a case-control studyMethylation marker selection. A Significant difference of methylation levels between ESCA tissues and paired adjacent tissues. B Gene ontology enrichment analyses of the genes containing significantly hypomethylated or hypermethylated MDRs. C Heatmap illustrating the hypomethylated and the hypermethylated DMRs between ESCA tissues and adjacent tissues. D Scatter diagram exhibiting the distribution of methylation region value between the ESCA tissues and paired adjacent tissues. Abbreviations: DMR, differentially methylated region; ESCA, esophageal cancerBack to article page