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Table 2 Sensitivity and specificity in the training set and test set

From: Discovery and validation of methylation signatures in circulating cell-free DNA for early detection of esophageal cancer: a case-control study

Patient group

Training set

Test set

Tested

Positive

Sensitivity (%)

Specificity (%)

Tested

Positive

Sensitivity (%)

Specificity (%)

Early stage

23

19

82.6% (61.2–95.0%)

 

26

17

65.4% (44.3–82.8%)

 

Late stage

20

18

90.0% (68.3–98.8%)

 

16

15

93.8% (69.8–99.8%)

 

All cancer

43

37

86.0% (72.2–94.8%)

 

42

32

76.2% (60.5–87.9%)

 

Benign

5

1

20.0% (0.5–71.4%)

80.0% (28.4–99.5%)

5

1

20.0% (0.5–71.4%)

80.0% (28.4–99.5%)

Healthy control

62

3

 

95.2% (86.5–99.0%)

63

3

 

95.2% (86.7–99.0%)

All non-cancer

67

4

 

94.0% (85.5–98.3%)

68

4

 

94.1% (85.7–98.4%)