Fig. 6

Sensitivity analyses. A Sensitivity of the primary outcome (TB-related deaths averted over 10 years by a combined intervention of a one-time campaign plus health system strengthening), to individual model parameters. Each pair of boxplots shows variation in the outcome when the analysis was limited to either simulations in which the value of the parameter of interest was in the top (light pink) or bottom (dark green) decile of its values across all accepted simulations. In each boxplot, the edges of the box represent the lower and upper interquartile range, the band in the middle represents the median, and the end of the whiskers represent 2.5th and 97.5th percentiles. The vertical dotted line shows the median across all accepted simulations. B, C Contours show the proportion of TB deaths averted by year 1 (B) and by year 10 (C) after a one-time campaign (with no subsequent health system strengthening) that achieves cure of LTBI in the proportion of the population indicated on the x-axis and cure of active TB in the proportion indicated on the y-axis. D Colored level surfaces indicate the additional impact on mortality of including health system strengthening measures with a one-time campaign, relative to the impact of the one-time campaign alone, assuming 70% coverage with one-time intervention, and a specified percentage reduction in unsuccessful treatments (x-axis) and diagnostic delays (y-axis). The red cross in B–D indicates the reference scenario. Please see Additional file 1: Fig. S-2 for the sensitivity of the secondary outcome, TB cases averted over 10 years