Table 1 Characteristics of participants with genetic information in CKB and UKB
No. (%)a | CKB | UKB | ||
|---|---|---|---|---|
Characteristic | No incident HF (n = 94,563) | Incident HF (n = 1 451) | No incident HF (n = 332,613) | Incident HF (n = 3169) |
Age, mean (SD), y | 52.7 (10.9) | 62.7 (8.9) | 56.0 (8.1) | 61.8 (6.2) |
Sex | ||||
 Male | 40,395 (42.7) | 691 (47.6) | 152,147 (45.7) | 2030 (64.1) |
 Female | 54,168 (57.3) | 760 (52.4) | 180,466 (54.3) | 1136 (35.9) |
Socioeconomic statusb | ||||
 Low | 29,435 (31.1) | 656 (45.2) | 66,262 (19.9) | 879 (27.8) |
 Intermediate | 28,261 (29.9) | 369 (25.4) | 199,545 (60.0) | 1739 (54.9) |
 High | 36,867 (39.0) | 426 (29.4) | 66,806 (20.1) | 548 (17.3) |
Healthy lifestyle factors | ||||
 Currently not smoking | 65,152 (68.9) | 864 (59.6) | 298,678 (89.8) | 2635 (83.2) |
 Not excessive drinking | 87,302 (92.3) | 1346 (92.8) | 165,902 (49.9) | 1965 (62.1) |
 Active physical activity | 44,662 (47.2) | 490 (33.8) | 239,307 (72.0) | 351 (11.1) |
 Healthy diet | 6264 (6.6) | 75 (5.2) | 289,401 (87.0) | 1365 (43.1) |
 Normal BMI and WC | 47,306 (50.0) | 708 (48.8) | 109,555 (32.9) | 608 (19.2) |
Optimal cardiometabolic factors | ||||
 Ideal blood pressure | 25,319 (26.8) | 192 (13.2) | 40,554 (12.2) | 179 (5.7) |
 Ideal blood glucose | 82,566 (87.3) | 1191 (82.1) | 285,859 (85.9) | 2327 (73.5) |
 Ideal blood lipid | 94,429 (99.9) | 1445 (99.6) | 106,983 (32.2) | 1391 (43.9) |
ICVHMs | Â | Â | Â | Â |
 Unfavorable | 2267 (2.4) | 62 (4.3) | 14,171 (4.3) | 735 (23.2) |
 Intermediate | 66,034 (69.8) | 1184 (81.6) | 239,771 (72.1) | 939 (29.7) |
 Favorable | 26,262 (27.8) | 205 (14.1) | 78,671 (23.7) | 881 (27.8) |
Weighted genetic risk categoryc | ||||
 Low | 40,176 (42.5) | 590 (40.7) | 118,849 (35.7) | 1056 (33.3) |
 Intermediate | 23,117 (24.5) | 340 (23.4) | 116,045 (34.9) | 1122 (35.4) |
 High | 31,270 (33.1) | 521 (35.9) | 97,719 (29.4) | 988 (31.2) |