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Table 1 Basic characteristics of the SMA and SSA groups

From: Comparison of submucosal and subserosal approaches toward optimized indocyanine green tracer-guided laparoscopic lymphadenectomy for patients with gastric cancer (FUGES-019): a randomized controlled trial

Characteristic

Mean (SD)/No. (%)

P value

SMA (n = 130)

SSA (n = 129)

Age, years

58.8 (11.3)

59.0 (10.3)

0.886

BMI, kg/m2

22.5 (3.2)

22.3 (3.1)

0.738

Sex

 Male

87 (66.9)

88 (68.2)

0.824

 Female

43 (33.1)

41 (31.8)

ECOG performance status

 0

107 (82.3)

107 (82.9)

0.892

 1

23 (17.7)

22 (17.1)

Tumor location

 Upper

27 (20.8)

21 (16.3)

0.527

 Middle

31 (23.8)

37 (28.7)

 Lower

72 (55.4)

71 (55.0)

Surgical procedure

 Distal gastrectomy

71 (54.6)

65 (50.4)

0.496

 Total gastrectomy

59 (45.4)

64 (49.6)

Reconstruction

 Billroth I

5 (3.8)

10 (7.8)

0.239

 Billroth II

66 (50.8)

55 (42.6)

 Roux-en-Y

59 (45.4)

64 (49.6)

Histology

 Differentiated

55 (42.3)

57 (44.2)

0.760

 Undifferentiated

75 (57.7)

72 (55.8)

Lymphvascular invasion

 Negative

74 (56.9)

80 (62.0)

0.404

 Positive

56 (43.1)

49 (38.0)

Size, cm

 ≤ 4

75 (57.7)

83 (64.3)

0.273

 > 4

55 (42.3)

46 (35.7)

cT category

 cT1

41 (31.5)

46 (35.7)

0.871

 cT2

19 (14.6)

16 (12.4)

 cT3

42 (32.3)

42 (32.6)

 cT4a

28 (21.5)

25 (19.4)

cN category

 cN0

52 (40.0)

57 (44.2)

0.495

 cN+

78 (60.0)

72 (55.8)

pT category

 pT1

39 (30.0)

47 (36.4)

0.528

 pT2

19 (14.6)

13 (10.1)

 pT3

48 (36.9)

43 (33.3)

 pT4a

24 (18.5)

26 (20.2)

pN category

 pN0

52 (40.0)

58 (45.0)

0.942

 pN1

27 (20.8)

24 (18.6)

 pN2

23 (17.7)

20 (15.5)

 pN3a

20 (15.4)

20 (15.5)

 pN3b

8 (6.2)

7 (5.4)

AJCC 8th pTNM staging

 I

46 (35.4)

49 (38.0)

0.767

 II

34 (26.2)

36 (27.9)

 III

50 (38.5)

44 (34.2)

CEA, ng/ml

 < 5

110 (84.6)

104 (80.6)

0.396

 ≥ 5

20 (15.4)

25 (19.4)

CA19-9, U/ml

 < 37

110 (84.6)

112 (86.8)

0.612

 ≥ 37

20 (15.4)

17 (13.2)

CA72-4, U/ml

 < 6.9

120 (92.3)

116 (89.9)

0.500

 ≥ 6.9

10 (7.7)

13 (10.1)

AFP, ng/ml

 < 20

128 (98.5)

125 (96.9)

0.403

 ≥ 20

2 (1.5)

4 (3.1)

CA125, U/ml

 < 35

127 (97.7)

126 (97.7)

0.992

 ≥ 35

3 (2.3)

3 (2.3)

  1. AJCC American Joint Committee on Cancer, BMI body mass index (calculated as weight in kilograms divided by height in meters squared), ECOG Eastern Cooperative Oncology, LN lymph node, CEA carcinoembryonic antigen, CA199 carbohydrate antigen 19-9, CA72-4 carbohydrate antigen 72-4, AFP alpha fetoprotein, CA125 carbohydrate antigen 125, SMA submucosa approach, SSA subserosa approach, SD standard deviation