Fig. 5

Ratio of cases averted by annual RISK11 targeted preventive therapy compared to universal treatment by prevalence of infection (x-axis) and annual risk of infection (y-axis). Left panel: after 5 years; right panel: after 10 years. Black lines show the contour where the ratio = 1. Black dots indicate the median prevalence and ARI assumed in the CORTIS-HR cohort (Fig. 2)