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Table 2 Covariate analysis for symptom development rate for Kenya and Blantyre. Asymptomatic, symptomatic and total TB duration by sex, age and HIV status for Kenya and Blantyre, Malawi (RR = risk ratio)

From: Durations of asymptomatic, symptomatic, and care-seeking phases of tuberculosis disease with a Bayesian analysis of prevalence survey and notification data

   

Asymptomatic

duration, month

Symptom onset rate after TB activation, per year

Symptomatc

duration, month

Total

duration, month

Crude rate

Crude RR

Adjusted RR

Kenya

Overall

 

8.3 (6.8–10.1)

1.25 (1.05–1.50)

  

8.4 (7.1– 9.7)

16.7 (14.5–19.1)

Sex

Female

8.1 (6.2–10.3)

1.30 (1.01–1.69)

Reference

Reference

7.2 (5.8–8.8)

15.4 (13.0–18.1)

Male

9.0 (7.2–11.2)

1.14 (0.93–1.40)

0.89 (0.63–1.20)

0.68 (0.50–0.89)

9.7 (8.2–11.5)

18.8 (16.1–21.8)

Age

(15,25)

9.5 (6.6–13.0)

1.11 (0.76–1.60)

reference

reference

10.4 (7.9–13.2)

20.0 (16.1–24.4)

(25,35)

8.6 (6.3–11.4)

1.23 (0.90–1.66)

1.13 (0.75–1.67)

1.20 (0.77–1.69)

9.4 (7.5–11.5)

18.0 (15.0–21.6)

(35,45)

7.1 (5.0– 9.7)

1.55 (1.08–2.22)

1.43 (0.87–2.17)

1.72 (1.10–2.54)

7.7 (5.9– 9.7)

14.7 (11.9–18.1)

(45,55)

7.4 (4.8–10.7)

1.49 (0.94–2.31)

1.39 (0.80–2.43)

1.82 (0.95–3.17)

8.3 (6.0–11.1)

15.7 (12.4–19.7)

(55,65)

9.6 (6.1–13.7)

1.10 (0.70–1.74)

1.02 (0.55–1.72)

1.23 (0.68–2.06)

5.2 (3.1–8.3)

14.8 (10.9–19.4)

(65,Inf)

7.1 (4.6–10.2)

1.52 (0.97–2.35)

1.43 (0.80–2.55)

1.42 (0.89–2.34)

5.3 (3.4–7.7)

12.4 (9.4–16.0)

HIV

Non-HIV

9.8 (7.9–12.2)

1.03 (0.85–1.25)

Reference

Reference

9.9 (8.5–11.7)

19.7 (17.1–23.0)

PLHIV

3.8 (2.4–5.6)

3.09 (1.96–4.80)

2.88 (1.82–4.54)

2.45 (1.45–3.68)

4.0 (2.5–5.7)

7.8 (5.8–10.2)

Blantyre

Overall

 

3.8 (2.3–5.8)

3.10 (1.86–4.98)

  

3.7 (2.3–5.4)

7.5 (5.4–10.1)

Sex

Female

3.5 (1.3–6.2)

3.90 (1.73–8.83)

reference

reference

3.1 (1.3–5.5)

6.6 (3.5–10.2)

Male

4.9 (2.6–7.9)

2.46 (1.34–4.48)

0.82 (0.29–1.82)

0.81 (0.30–1.71)

5.0 (2.9–7.7)

9.9 (6.7–13.8)

Age

(15,50)

4.0 (2.3–6.2)

3.00 (1.74–5.03)

reference

reference

3.7 (2.1–5.6)

7.7 (5.3–10.3)

(50,Inf)

3.5 (1.1–7.1)

4.17 (1.46–10.84)

1.53 (0.45–3.94)

1.41 (0.47–4.16)

4.6 (1.9–8.1)

8.1 (4.3–12.5)

HIV

Non-HIV

8.5 (5.0–12.7)

1.29 (0.76–2.16)

reference

reference

7.1 (4.3–10.8)

15.6 (11.3–20.8)

PLHIV

1.3 (0.3–3.0)

12.79 (3.77–41.16)

5.33 (1.90–11.92)

4.81 (1.65–12.82)

2.4 (1.0–4.1)

3.7 (1.9–6.0)

  1. RR risk ratio, PLHIV people living with HIV