Fig. 3

Associations between genetically determined standardized TSH and fT4 within the reference range and coronary artery disease (91,810 CAD cases and 656,091 controls of European ancestry). Odds ratios (ORs) shown (per 1 s.d. increase in TSH/fT4 concentration) are inverse variance-weighted (IVW) estimate, MR Egger, and weighted-median estimator; error bars indicate 95% confidence intervals