Fig. 2

Bubble plots with locally weighted scatterplot smoothing for dose-response relationships between the level of socioeconomic deprivation and the relative alcohol-attributable mortality risk (RR, shown on the log scale) by indicator of socioeconomic status and sex (women in light blue, men in dark blue), using inverse variance weights. All pairwise comparisons reported in a study were included (unit of observation). The level of socioeconomic deprivation is coded as the midpoint of the percentile range in the cumulative SES distribution with 0=lowest level of socioeconomic deprivation and 100=highest level of socioeconomic deprivation. Triangles indicate reference groups, and bubbles show the RR point estimates according to their weight. The gray-shaded areas indicate the 95% confidence intervals around the locally weighted scatterplot smoothing lines