Fig. 4
From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease
The establishment of the predictive model. The panel of the seven serum miRNAs was linearly correlated with the P-tau/Aβ42 ratio in CSF and predicted the P-tau/Aβ42 ratios in the patients with AD in Datasets 2 (a) and 3 (b). The predicted P-tau/Aβ42 was significantly increased in patients with AD in Datasets 2 (c) and 3 (d) and performed well in differentiating patients with AD from controls in Datasets 2 (e) and 3 (f). Abbreviations: AUC, area under the curve; AD, Alzheimer’s disease. The dotted line in c and d is cutoff value (0.14)