From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease
Characteristic | Total sample (n = 44) | Controls (n = 21) | AD (n =23) |
---|---|---|---|
Age, median (25th–75th percentile) | 69 (66–73) | 69 (67–72) | 72 (65–73) |
Education year, median (25th–75th percentile) | 9 (7–11) | 10 (8–11) | 9 (7–10) * |
Women, No. (%) | 23 (52.3) | 12 (52.2) | 11 (52.4) |
ApoE ε4 positive (%) | 13 (29.5) | 4 (17.4) | 9 (42.9) * |
MMSE score (SD) | 25.2 (4.1) | 28.7 (0.8) | 22.0 (3.1) * |
Aβ42, mean (SD), pg/ml | 572.8 (186.4) | 740.1 (118.6) | 420.1 (63.1) |
T-tau, mean (SD), pg/ml | 443.3 (206.6) | 297.1 (100.2) | 576.7 (187.9) |
P-tau, mean (SD), pg/ml | 104.9 (76.9) | 52.9 (20.4) | 152.5 (79.2) |