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Table 1 Characteristics of participants in Dataset 1

From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease

Characteristic Total sample
(n = 44)
Controls
(n = 21)
AD
(n =23)
Age, median (25th–75th percentile) 69 (66–73) 69 (67–72) 72 (65–73)
Education year, median (25th–75th percentile) 9 (7–11) 10 (8–11) 9 (7–10) *
Women, No. (%) 23 (52.3) 12 (52.2) 11 (52.4)
ApoE ε4 positive (%) 13 (29.5) 4 (17.4) 9 (42.9) *
MMSE score (SD) 25.2 (4.1) 28.7 (0.8) 22.0 (3.1) *
Aβ42, mean (SD), pg/ml 572.8 (186.4) 740.1 (118.6) 420.1 (63.1)
T-tau, mean (SD), pg/ml 443.3 (206.6) 297.1 (100.2) 576.7 (187.9)
P-tau, mean (SD), pg/ml 104.9 (76.9) 52.9 (20.4) 152.5 (79.2)
  1. The values of age, education year, and MMSE are shown as mean (SD)
  2. Abbreviations: AD, Alzheimer’s disease; VaD, vascular dementia; PDD, Parkinson disease dementia; bvFTD, behavioral variant frontotemporal dementia; DLB, dementia with Lewy body; ApoE ε4, apolipoprotein ε4; MMSE, Mini-Mental State Examination; SD, standard deviation
  3. *P < 0.05 compared to controls