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Table 2 Characteristics of participants in Dataset 2

From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease

Characteristic Total Sample
(n = 406)
Controls
(n = 216)
AD
(n =190)
Age, median (25th–75th percentile) 68 (63–71) 67 (63–72) 68 (64–71)
Education year, median (25th–75th percentile) 10 (8–11) 10.0 (9–11) 9 (8–10)*
Women, No. (%) 211 (52.0) 112 (51.9) 99 (52.1)
ApoE ε4 positive (%) 120 (29.6) 41 (19.0) 79 (41.6)*
MMSE score (SD) 24.9 (4.7) 29.0 (1.0) 20.3 (2.4)*
Aβ42, mean (SD), pg/ml 555.5 (199.6) 711.3 (130.7) 378.2 (81.3)
T-tau, mean (SD), pg/ml 460.9 (206.1) 382.3 (98.9) 611.7 (192.1)
P-tau, mean (SD), pg/ml 70.6 (33.1) 52.3 (20.6) 91.4 (32.3)
  1. The values of age, education year, and MMSE are shown as mean (SD)
  2. Abbreviations: AD, Alzheimer’s disease; VaD, vascular dementia; PDD, Parkinson disease dementia; bvFTD, behavioral variant frontotemporal dementia; DLB, dementia with Lewy body; ApoE ε4, apolipoprotein ε4; MMSE, Mini-Mental State Examination; SD, standard deviation
  3. *P < 0.05 compared to controls