From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease
Characteristic | Total Sample (n = 406) | Controls (n = 216) | AD (n =190) |
---|---|---|---|
Age, median (25th–75th percentile) | 68 (63–71) | 67 (63–72) | 68 (64–71) |
Education year, median (25th–75th percentile) | 10 (8–11) | 10.0 (9–11) | 9 (8–10)* |
Women, No. (%) | 211 (52.0) | 112 (51.9) | 99 (52.1) |
ApoE ε4 positive (%) | 120 (29.6) | 41 (19.0) | 79 (41.6)* |
MMSE score (SD) | 24.9 (4.7) | 29.0 (1.0) | 20.3 (2.4)* |
Aβ42, mean (SD), pg/ml | 555.5 (199.6) | 711.3 (130.7) | 378.2 (81.3) |
T-tau, mean (SD), pg/ml | 460.9 (206.1) | 382.3 (98.9) | 611.7 (192.1) |
P-tau, mean (SD), pg/ml | 70.6 (33.1) | 52.3 (20.6) | 91.4 (32.3) |