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Table 2 Characteristics of participants in Dataset 2

From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease

Characteristic

Total Sample

(n = 406)

Controls

(n = 216)

AD

(n =190)

Age, median (25th–75th percentile)

68 (63–71)

67 (63–72)

68 (64–71)

Education year, median (25th–75th percentile)

10 (8–11)

10.0 (9–11)

9 (8–10)*

Women, No. (%)

211 (52.0)

112 (51.9)

99 (52.1)

ApoE ε4 positive (%)

120 (29.6)

41 (19.0)

79 (41.6)*

MMSE score (SD)

24.9 (4.7)

29.0 (1.0)

20.3 (2.4)*

Aβ42, mean (SD), pg/ml

555.5 (199.6)

711.3 (130.7)

378.2 (81.3)

T-tau, mean (SD), pg/ml

460.9 (206.1)

382.3 (98.9)

611.7 (192.1)

P-tau, mean (SD), pg/ml

70.6 (33.1)

52.3 (20.6)

91.4 (32.3)

  1. The values of age, education year, and MMSE are shown as mean (SD)
  2. Abbreviations: AD, Alzheimer’s disease; VaD, vascular dementia; PDD, Parkinson disease dementia; bvFTD, behavioral variant frontotemporal dementia; DLB, dementia with Lewy body; ApoE ε4, apolipoprotein ε4; MMSE, Mini-Mental State Examination; SD, standard deviation
  3. *P < 0.05 compared to controls