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Table 3 Characteristics of participants in Dataset 3

From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease

Characteristic

Total Sample

(n = 304)

Controls

(n = 153)

AD

(n =151)

Age, median (25th–75th percentile)

69 (64–72)

68 (64–72)

69 (65–73)

Education year, median (25th–75th percentile)

10 (8–11)

10 (9–11)

9 (7–10)*

Women, No. (%)

155 (50.9)

78 (50.9)

77 (50.9)

ApoE ε4 positive (%)

90 (29.6)

28 (18.3)

62 (41.1)*

MMSE score (SD)

25.0 (4.5)

29.0 (0.6)

20.9 (2.8)*

Aβ42, mean (SD), pg/ml

559.2 (213.4)

742.6 (128.2)

373.4 (79.2)

T-tau, mean (SD), pg/ml

478.7 (212.9)

322.2 (98.6)

637.3 (177.2)

P-tau, mean (SD), pg/ml

73.4 (36.8)

55.7 (24.2)

91.3 (38.7)

  1. The values of age, education year, and MMSE are shown as mean (SD)
  2. Abbreviations: AD, Alzheimer’s disease; VaD, vascular dementia; PDD, Parkinson disease dementia; bvFTD, behavioral variant frontotemporal dementia; DLB, dementia with Lewy body; ApoE ε4, apolipoprotein ε4; MMSE, Mini-Mental State Examination; SD, standard deviation
  3. *P < 0.05 compared to controls