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Table 3 Characteristics of participants in Dataset 3

From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease

Characteristic Total Sample
(n = 304)
Controls
(n = 153)
AD
(n =151)
Age, median (25th–75th percentile) 69 (64–72) 68 (64–72) 69 (65–73)
Education year, median (25th–75th percentile) 10 (8–11) 10 (9–11) 9 (7–10)*
Women, No. (%) 155 (50.9) 78 (50.9) 77 (50.9)
ApoE ε4 positive (%) 90 (29.6) 28 (18.3) 62 (41.1)*
MMSE score (SD) 25.0 (4.5) 29.0 (0.6) 20.9 (2.8)*
Aβ42, mean (SD), pg/ml 559.2 (213.4) 742.6 (128.2) 373.4 (79.2)
T-tau, mean (SD), pg/ml 478.7 (212.9) 322.2 (98.6) 637.3 (177.2)
P-tau, mean (SD), pg/ml 73.4 (36.8) 55.7 (24.2) 91.3 (38.7)
  1. The values of age, education year, and MMSE are shown as mean (SD)
  2. Abbreviations: AD, Alzheimer’s disease; VaD, vascular dementia; PDD, Parkinson disease dementia; bvFTD, behavioral variant frontotemporal dementia; DLB, dementia with Lewy body; ApoE ε4, apolipoprotein ε4; MMSE, Mini-Mental State Examination; SD, standard deviation
  3. *P < 0.05 compared to controls