From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease
Characteristic | Total Sample (n = 304) | Controls (n = 153) | AD (n =151) |
---|---|---|---|
Age, median (25th–75th percentile) | 69 (64–72) | 68 (64–72) | 69 (65–73) |
Education year, median (25th–75th percentile) | 10 (8–11) | 10 (9–11) | 9 (7–10)* |
Women, No. (%) | 155 (50.9) | 78 (50.9) | 77 (50.9) |
ApoE ε4 positive (%) | 90 (29.6) | 28 (18.3) | 62 (41.1)* |
MMSE score (SD) | 25.0 (4.5) | 29.0 (0.6) | 20.9 (2.8)* |
Aβ42, mean (SD), pg/ml | 559.2 (213.4) | 742.6 (128.2) | 373.4 (79.2) |
T-tau, mean (SD), pg/ml | 478.7 (212.9) | 322.2 (98.6) | 637.3 (177.2) |
P-tau, mean (SD), pg/ml | 73.4 (36.8) | 55.7 (24.2) | 91.3 (38.7) |