Table 4 Characteristics of participants in Dataset 4
From: Prediction of P-tau/Aβ42 in the cerebrospinal fluid with blood microRNAs in Alzheimer’s disease
Characteristic | Total Sample (n = 503) | Controls (n = 139) | AD (n =155) | aMCI (n =55) | VaD (n =51) | PDD (n =53) | bvFTD (n =53) | DLB (n =52) |
|---|---|---|---|---|---|---|---|---|
Age, median (25th–75th percentile) | 67 (63–72) | 67 (65–73) | 68 (63–73) | 67 (64–70) | 67 (63–70) | 68 (64–73) | 66 (62–70) | 66 (62–70) |
Education year, median (25th–75th percentile) | 9 (8–11) | 10 (9–11) | 9 (8–10) | 10 (8–12) | 10 (8–11) | 9 (8–10) | 10.0 (9–11) | 9.0 (7–11) |
Women, No. (%) | 255 (50.7) | 71 (51.1) | 79 (51.0) | 28 (50.1) | 24 (47.1) | 26 (49.1) | 28 (52.8) | 27 (51.9) |
ApoE ε4 positive (%) | 133 (26.4) | 25 (18.0) | 64 (41.3)* | 15 (27.3) | 13 (25.5)* | 10 (18.9) | 11 (20.8) | 10 (19.2) |
MMSE score (SD) | 23.4 (4.5) | 29.1 (0.57) | 20.8 (3.2)* | 26.4 (0.6) | 21.5 (2.9)* | 21.0 (3.2)* | 21.9 (3.0)* | 21.8 (3.6)* |
Aβ42, mean (SD), pg/ml | 581.2 (184.7) | 683.5 (135) | 371.6 (80.7)* | 507.3 (134.1)* | 705 (108.5) | 700.6 (127.6) | 678.8 (141.5) | 667.6 (142.4) |
T-tau, mean (SD), pg/ml | 449.2 (166.6) | 340.1 (93.6) | 595.6 (187.1) | 474.3 (130.9) | 395.5 (91.6) | 359.2 (107.8) | 448.6 (110.7) | 422.6 (113.4) |
P-tau, mean (SD), pg/ml | 63.2 (31.5) | 50.1 (19.5) | 90.6 (37.7)* | 65.6 (21.8)* | 48.9 (17.7) | 49 (13.5) | 53 (22.6) | 53.2 (25.1) |