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Fig. 4 | BMC Medicine

Fig. 4

From: m6A regulator expression profile predicts the prognosis, benefit of adjuvant chemotherapy, and response to anti-PD-1 immunotherapy in patients with small-cell lung cancer

Fig. 4

m6A score distribution and survival of patients in multiple validation cohorts. A The m6A score distribution with patient survival status in the Shanghai cohort. The red colour indicates deceased patients while blue indicates survivors. Expression distribution of the five regulators, with red colour indicating higher expression and blue indicating lower expression. B Kaplan-Meier curves of OS in 47 patients from the Shanghai cohort based on the m6A score. C ROC analysis of m6A score for survival prediction at 1, 3, and 5 years in the Shanghai cohort. D C-index values of the m6A score and clinicopathological parameters for OS in the Shanghai cohort. E The m6A score distribution with patient survival status in the NCC cohort. Expression distribution of the five regulators in the NCC cohort. F Kaplan-Meier curves of OS in 150 patients of the NCC cohort based on the m6A score. G ROC analysis of the m6A score for predicting survival at 1, 3, and 5 years in the NCC cohort. H C-index values of m6A score and clinicopathological parameters for OS in the NCC cohort. I The m6A score distribution with patient recurrence status in the NCC cohort, red indicating tumour recurrence while blue indicates no-recurrence. Expression distribution of the five regulators in the NCC cohort, with red colour indicating higher expression and blue indicating lower expression. J Kaplan-Meier curves of RFS in 150 patients of the NCC cohort based on m6A score. K ROC analysis of m6A score for the prediction of RFS at 1, 3, and 5 years in the NCC cohort. H C-index values of m6A score and clinicopathological parameters for RFS in the NCC cohort

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