|
Study characteristics
|
|
- Specification of the target trial
|
2 (3)
|
|
- Using a diagram to illustrate study design
|
14 (18)
|
|
Eligibility criteria
|
|
- Inclusion criteria for the study
|
76 (99)
|
|
- Post-baseline events in inclusion criteria (e.g., use of treatment, no follow-up data)
|
9 (12)
|
|
- Exclusion of individuals with contraindications for interventions evaluated
|
9 (12)
|
|
Adjustment for confounders
|
|
- Propensity score
|
60 (70)
|
|
- Inverse probability weighting
|
10 (12)
|
|
- Multivariable regression
|
15 (17)
|
|
- Instrumental variable
|
2 (2)
|
|
Outcome
|
|
- Primary outcome reported
|
77 (100)
|
|
Causal contrast of interests
|
|
- Intention-to-treat effect
|
11 (14)
|
|
- Per-protocol effect
|
6 (8)
|
|
- Both
|
10 (13)
|
|
- Not specified
|
50 (65)
|
|
Key time point of the target trial
|
|
- Time point of the start of follow-up
|
72 (94)
|
|
- Time point of eligibility criteria
|
72 (94)
|
|
- Time point of treatment assignment
|
68 (88)
|
|
- All three time points
|
63 (81)
|
