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Table 3 Reporting of essential information

From: Risk of bias in observational studies using routinely collected data of comparative effectiveness research: a meta-research study

Reporting of essential information

N = 77 (%)

Study characteristics

 - Specification of the target trial

2 (3)

 - Using a diagram to illustrate study design

14 (18)

Eligibility criteria

 - Inclusion criteria for the study

76 (99)

 - Post-baseline events in inclusion criteria (e.g., use of treatment, no follow-up data)

9 (12)

 - Exclusion of individuals with contraindications for interventions evaluated

9 (12)

Adjustment for confounders

 - Propensity score

60 (70)

 - Inverse probability weighting

10 (12)

 - Multivariable regression

15 (17)

 - Instrumental variable

2 (2)

Outcome

 - Primary outcome reported

77 (100)

Causal contrast of interests

 - Intention-to-treat effect

11 (14)

 - Per-protocol effect

6 (8)

 - Both

10 (13)

 - Not specified

50 (65)

Key time point of the target trial

 - Time point of the start of follow-up

72 (94)

 - Time point of eligibility criteria

72 (94)

 - Time point of treatment assignment

68 (88)

 - All three time points

63 (81)