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Table 1 Characteristics of MetS cases and controlsa in FAMILY

From: Metabolite profiles and the risk of metabolic syndrome in early childhood: a case-control study

Characteristic

MetS caseb (n = 228)

MetS control (n = 228)

Overall (n = 456)

Age (years)

5.14 (0.28)

5.16 (0.29)

5.15 (0.29)

Sex (female)

115 (50.4%)

115 (50.4%)

230 (50.4%)

Daily night sleep (hours)

10.88 (0.65)

10.93 (0.61)

10.90 (0.63)

Physical activity (weighted daily minutes)

237 (71)

227 (71)

232 (71)

Diet quality Index

− 0.82 (3.4)

− 1.37 (3.45)

− 1.1 (3.43)

Social disadvantage index

 Low (0–1)

164 (73.5%)

163 (75.1%)

327 (74.0%)

 Moderate (2–3)

43 (19.3%)

48 (22.1%)

91 (21.0%)

 High (4–5)

16 (7.2%)

6 (2.8%)

22 (5.0%)

Screen time exposure

 Low exposure (< 2 h)

53 (23.3%)*

71 (31.8%)

124 (28.0%)

 High exposure (≥ 2 h)

174 (76.7%)*

152 (68.2%)

326 (72.0%)

Systolic blood pressure (mm Hg)

101.30 (8.31)***

97.37 (8.03)

99.33 (8.40)

Diastolic blood pressure (mm Hg)

61.18 (5.44)***

59.25 (5.42)

60.21 (5.51)

Total cholesterol (mmol/L)

4.13 (0.65)

4.07 (0.72)

4.10 (0.69)

HDL cholesterol (mmol/L)

1.43 (0.32)*

1.37 (0.31)

1.40 (0.31)

LDL cholesterol (mmol/L)

2.38 (0.61)

2.37 (0.63)

2.37 (0.62)

Triglycerides (mmol/L)

0.71 (0.31)

0.69 (0.29)

0.70 (0.30)

Fasting blood glucose (mmol/L)

4.75 (0.38)***

4.52 (0.31)

4.63 (0.37)

BMI (kg/m2)

16.66 (1.80)***

15.13 (0.90)

15.89 (1.62)

BMI-for-age z-score (WHO)

0.84 (1.01)***

− 0.12 (0.64)

0.36 (0.97)

Waist circumference (cm)

53.43 (4.47)***

49.97 (2.59)

51.70 (4.04)

Waist circumference-to-height

0.48 (0.04)***

0.45 (0.02)

0.47 (0.03)

Sum of skinfolds (mm)

20.50 (6.78)***

16.80 (4.14)

18.63 (5.91)

z-BMI ≥ 75th percentile AND waist circumference ≥ 90th percentile

45 (19.7%)

0 (0%)

45 (9.9%)

z-BMI ≥75th percentile AND median ≤ waist circumference < 90th percentile

89 (39.0%)

0 (0%)

89 (19.5%)

z-BMI ≥75th percentile AND systolic blood pressure ≥ 90th percentile

22 (9.7%)

0 (0%)

22 (4.8%)

Fasting glucose ≥ 90th percentile

70 (30.7%)

0 (0%)

70 (15.4%)

Maternal GDM

75 (32.9%)

0 (0%)

75 (16.4%)

  1. Values are presented as mean (SD) or n (%). aAge- and sex-matched 1:1 with control children. bStatistical comparisons between MetS cases and controls assuming equal (t test) or unequal variance (Welch’s t test) were performed as appropriate for continuous variables; Fisher exact tests were used for categorical variables. *p < 0.05, **p < 0.01, ***p < 0.001