No lithium n=9140 | Lithium use n=412 | |||
---|---|---|---|---|
n (%) | n (%) | Relative risk (95% confidence interval) | ||
Crude | Adjusted | |||
Preeclampsia | 286 (3.1) | 15 (3.6) | 1.16 (0.70, 1.94) | 0.95 (0.54, 1.64) |
Spontaneous preterm birth | 314 (3.4) | 33 (8.0) | 2.33 (1.62, 3.34) | 2.34 (1.55, 3.56) |
Small for gestational age | 235 (2.6) | 12 (2.9) | 1.13 (0.59, 2.18) | 1.05 (0.50, 2.19) |
Large for gestational age | 374 (4.1) | 39 (9.5) | 2.32 (1.68, 3.18) | 2.28 (1.61, 3.23) |
Secondary outcomes | ||||
Macrosomia | 42 (0.5) | 2 (0.5) | 1.06 (0.26, 4.35) | 1.16 (0.27, 4.96) |
Hypoglycaemia | 271 (3.0) | 22 (5.3) | 1.80 (1.18, 2.74) | 1.59 (1.01, 2.49) |
Five-minute Apgar < 6 | 175 (1.9) | 11 (2.7) | 1.07 (0.50, 2.72) | 1.07 (0.50, 2.28) |
Malformations (all) | 309 (3.4) | 18 (4.4) | 1.29 (0.81, 2.05) | 1.35 (0.82, 2.21) |
Cardiac malformations | 72 (0.8) | 8 (1.9) | 2.46 (1.20, 5.07) | 3.01 (1.38, 6.53) |
Perinatal death | 40 (0.4) | 2 (0.5) | 1.69 (0.41, 7.03) | 1.01 (0.14, 7.56) |