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Table 3 Effect of P-gp inducer sodium ferulate on maternal weight gain rate, fetal body, and placental weights

From: P-gp expression inhibition mediates placental glucocorticoid barrier opening and fetal weight loss

Group

Maternal weight gain rate (%)

Fetal body weight (g)

Placental weight (g)

Female

Male

Female

Male

Control

52.0±1.5

1.100±0.024

1.100±0.026

0.085 ± 0.0037

0.086 ± 0.0031

Caffeine

40.0±1.7**

0.850±0.026 *

0.870±0.030 *

0.072 ± 0.003 **

0.074 ± 0.0025 **

Sodium ferulate

52.0±1.5

1.100±0.063

1.200±0.062

0.090±0.0031

0.095 ± 0.0039

Caffeine + sodium ferulate

47.0±2.8#

0.990 ±0.062 ##

1.000±0.053 ##

0.088±0.0029 #

0.093 ± 0.0028 #

  1. *P<0.05, **P<0.01 vs. control; #P<0.05, ##P<0.01 vs. caffeine