Table 2 Baseline characteristicsa of people with polypharmacy (N = 1356) by cluster, ELSA 2012
| Â | Cluster 1 RAAS inhibitors | Cluster 2 Mental health drugs | Cluster 3 CNS drugs | Cluster 4 RAAS inhibitors + antithrombotics | Cluster 5 Antithrombotics |
|---|---|---|---|---|---|
(N = 194) % (N) | (N = 298) % (N) | (N = 387) % (N) | (N = 352) % (N) | (N = 125) % (N) | |
Age (years) mean (SD) | 70.9 (8.2) | 71.3 (9.4) | 70.3 (8.5) | 73.4 (8.2) | 75.2 (8.3) |
Women | 53.6 (104) | 61.1 (182) | 63.6 (246) | 41.8 (147) | 52.8 (66) |
Living with a partner | 71.1 (138) | 56.7 (169) | 64.9 (251) | 63.9 (225) | 52.8 (66) |
Diabetes mellitus | 46.9 (91) | 37.9 (113) | 25.1 (97) | 37.2 (131) | 32.8 (41) |
CHD | 12.9 (25) | 38.3 (114) | 14.2 (55) | 43.5 (153) | 39.2 (49) |
Stroke | 4.1 (8) | 20.1 (60) | 7.0 (27) | 14.8 (52) | 15.2 (19) |
Lung disease (including asthma) | 33.5 (65) | 28.2 (84) | 43.4 (168) | 20.7 (73) | 26.4 (33) |
Number of conditionsb median (IQR) | 3 (2) | 4 (2) | 3 (2) | 3 (2) | 3 (2) |
Functional impairmentc | 26.8 (52) | 52.0 (155) | 52.5 (203) | 28.7 (101) | 29.6 (37) |
Mobility difficultyd | 68.6 (133) | 88.9 (265) | 83.5 (323) | 71.6 (252) | 84.0 (105) |
Obesity | |||||
 High BMI and waist circumference | 50.5 (98) | 49.3 (147) | 40.1 (155) | 38.4 (135) | 40.0 (50) |
 Either high BMI or high waist circumference | 26.8 (52) | 25.2 (75) | 24.0 (93) | 27.3 (96) | 28.0 (35) |
Current smoker | 11.3 (22) | 16.8 (50) | 16.5 (64) | 9.4 (33) | 5.6 (7) |
Sleep <  7 or >  9 h | 38.7 (75) | 46.6 (139) | 53.8 (208) | 39.2 (138) | 49.6 (62) |
Low physical activity | 29.4 (57) | 48.0 (143) | 42.9 (166) | 31.8 (112) | 38.4 (48) |
Depressive symptoms 4+ | 7.7 (15) | 30.2 (90) | 24.6 (95) | 11.9 (42) | 11.2 (14) |