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Fig. 4 | BMC Medicine

Fig. 4

From: Common DNA methylation changes in biliary tract cancers identify subtypes with different immune characteristics and clinical outcomes

Fig. 4

Association between methylation cluster and mutational events in the EHSH cohort. A Clinicopathological and mutational data of the 99 BTC samples. B, C Associations of the methylation-based clusters with TMB (B) and CNV (C). D Association between anatomic location and mutational rate. E Associations of mutation with the methylation-based clusters and overall survival. BTC, biliary tract cancer; CCA, cholangiocarcinoma; CNV, copy number variation; DMR, differentially methylated region; GBC, gallbladder cancer; LASSO, least absolute shrinkage and selection operator; TMB, tumor mutational burden

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