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Fig. 5 | BMC Medicine

Fig. 5

From: Common DNA methylation changes in biliary tract cancers identify subtypes with different immune characteristics and clinical outcomes

Fig. 5

Association of global methylation changes with prognosis and immune characteristics in the TCGA-CHOL cohort. A Clinicopathological, methylation, and mutational data of 36 CCAs. B, C Associations of the cluster-based risk with overall survival (B) and progression-free interval (C). D–L Associations of the cluster-based risk with genomic alterations (D), immune subtype (E), the signatures for immune subtyping (F), BCR/TCR features (G), the mRNA expression of checkpoints (H), leukocyte fraction (I), the fractions of 22 immune cells (J), immune-related signatures (K), and angiogenesis signature (L). BCR, B cell receptor; CCA, cholangiocarcinoma; TCR, T cell receptor; TMB, tumor mutational burden; SNV, single nucleotide variation

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