Fig. 4From: Intracranial efficacy of alectinib in ALK-positive NSCLC patients with CNS metastases—a multicenter retrospective studya CNS TTP in patients with symptomatic and asymptomatic BM in cohort 1. CNS TTP for patients with symptomatic BM and patients with asymptomatic BM in cohort 1was NE vs NE, p = 0.394, HR = 3.1(95% CI: 0.12 to 79.0). b CNS TTP in patients with symptomatic and asymptomatic BM in cohort 2. CNS TTP for patients with symptomatic BM and patients with asymptomatic BM in cohort 2 was 21.5 m vs NE, p = 0.168, HR = 2.24 (95% CI: 0.65 to 7.7)Back to article page