Fig. 3
Nfx induces prolonged ventricular repolarization and reduces Itof. A ECG waveforms of Sham (black profile, upper panel) and Nfx (red profile, bottom panel) mice. B–F Mean values of (B) QRS, (C) QT, (D) QTc, (E) JT, and (F) TpTe interval duration of Sham (N = 5 mice) and Nfx (N = 7 mice). G Representative Itof traces recorded from one cardiomyocyte from Sham (left panel, black profile) and Nfx (right panel, red profile) mice. H I/V curves for Itof density obtained in myocytes from Sham (black line, n = 24 cells, N = 9 mice) and Nfx (red line, n = 21 cells, N = 7 mice) mice. Data are presented as mean ± SEM. *P < 0.05; **P < 0.01 and ***P < 0.001 vs. Sham