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Fig. 7 | BMC Medicine

Fig. 7

From: The anti-aging factor Klotho protects against acquired long QT syndrome induced by uremia and promoted by fibroblast growth factor 23

Fig. 7

Diagram representing the involvement of FGF23-Klotho axis in acquired long QT syndrome. CKD, chronic kidney disease; FGF23, fibroblast growth factor 23; Itof, fast transient outward potassium current; kl/kl, Klotho hypomorphic mice; Kv4.2, K+ channel 4.2 subunit; Nfx, nephrectomy; sKL, soluble Klotho; Tg-kl, Klotho overexpression mice

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