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Table 2 Number of inoculated sporozoite, incubation period, and time to relapse by volunteer

From: The empirical support for the radical cure strategy for eliminating Plasmodium vivax in China

Volunteer

No. inoculated sporozoite (estimate of semi-quantified data)

No. of infective mosquito bites

Incubation period (day)

Time to relapse (days)

1st relapse

2nd relapse

3rd relapse

4th relapse

5th relapse

ID1

2600

10

11

166

255

   

ID2

1100

5

11

242

285

   

ID3

600

3

13

218

    

ID4

300

1

13

197

244

   

ID5

1400

10

11

66

137

210

  

ID6

1100

7

10

54

134

187

240

297

ID7

400

5

12

217

277

369

  

ID8

500

3

11

100

184

213

264

315

ID9

100

1

12

228

282

332

  

ID10

100

1

12

208

278

   

ID11

700

10

14

195

251

   

ID12

900

7

12

160

202

   

ID13

900

4

14

55

183

234

  

ID14

900

3

14

185

    

ID15

100

1

14

No relapse

    

ID16

75

2

15

No relapse

    

ID17

30

2

16

85

230

280

  

ID18

10

2

284

No relapse

    

ID19

25

1

268

No relapse

    

ID20

1900

10

10

283

347

   

ID21

1100

7

10

295

339

   

ID22

700

5

14

299

341

   

ID23

700

3

10

270

    

ID24

25

1

10

269

332

   

GD1b(7 participants)

2710a (1000–8000, total 19000)

No data

13.8 (11–17)

247.7 (14 cases, 193–287)

314.6 (9 cases, 286–335)

398 ( 3 cases, 373,380,440)

459

 

GD2b(7 participants)

278a (150–800, total 1947)

 

14.1 (12–17)

GD3_1

20

No data

298

No relapse

    

GD3_2

23

No data

299

352

    

GD3_3

42

No data

322

353

    
  1. The number of sporozoites in the salivary glands of each infected mosquitos was graded on a scale of 1+ to 26+. The total number of inoculated sporozoites was calculated and served as a rough indicator of the infective inoculum (the source document used did not contain details of these calculations)
  2. aAveraged number of sporozoites among inoculation volunteers
  3. bGD1 and GD2 are not individual-level data. We only had access to the average value of each group with 7 participants